Retention of Human iPSC-Derived or Primary Cells Following Xenotransplantation into Rat Immune-Privileged Sites

Retention of Human iPSC-Derived or Primary Cells Following Xenotransplantation into Rat Immune-Privileged Sites

In regenerative medicine, experimental animal models are commonly used to study potential effects of human cells as therapeutic candidates. Although some studies describe certain cells, such as mesenchymal stromal cells (MSC) or human primary cells, as hypoimmunogenic and therefore unable to trigger...

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Bibliographic Details
Main Authors: Thomas Später, Giselle Kaneda, Melissa Chavez, Julia Sheyn, Jacob Wechsler, Victoria Yu, Patricia Del Rio, Dave Huang, Melodie Metzger, Wafa Tawackoli, Dmitriy Sheyn
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Bioengineering
Subjects:
xenotransplantation
intervertebral discs
mesenchymal stem cells
nucleus pulposus cells
inflammation
cell therapy
Online Access:https://www.mdpi.com/2306-5354/10/9/1049

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