N-glycolylneuraminic acid as a carbohydrate cancer biomarker

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

One of the forms of aberrant glycosylation in human tumors is the expression of N-glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in mammals, cytidine-5′-monophosphate-N-acetylneuraminic acid (CMAH), appears to be genetically inactivated in humans. Regardless, low lev...

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Bibliographic Details
Main Authors:	Jing Wang, Lucy K. Shewell, Christopher J. Day, Michael P. Jennings
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Series:	Translational Oncology
Subjects:	N-glycolylneuraminic acid Neu5Gc Cancer biomarker Detection Prognosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523323000293

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