Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice.

Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice.

Importin α1/KPNA1 is a member of the Importin α family widely present in the mammalian brain and has been characterized as a regulator of neuronal differentiation, synaptic functionality, and anxiety-like behavior. In humans, a de novo mutation of the KPNA1 (human Importin α5) gene has been linked w...

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Main Authors: Koki Sakurai, Taichi Itou, Makiko Morita, Emiko Kasahara, Tetsuji Moriyama, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Atsuo Sekiyama, Masahiro Oka, Takatoshi Hikida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0258364

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