The effect of intravenous low dose ketamine for reducing postoperative sore throat

BackgroundThis study was performed to evaluate the effectiveness of intravenous low dose ketamine for reducing the incidence and severity of postoperative sore throat (POST).MethodsThis was a prospective, randomized, double-blind clinical trial. The study population consisted of 70 patients between...

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Main Authors: Sun Young Park, Sang Hyun Kim, Jung Il Noh, Su Myoung Lee, Mun Gyu Kim, Sang Ho Kim, Si Young Ok, Soon Im Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2010-07-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-59-22.pdf
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author Sun Young Park
Sang Hyun Kim
Jung Il Noh
Su Myoung Lee
Mun Gyu Kim
Sang Ho Kim
Si Young Ok
Soon Im Kim
author_facet Sun Young Park
Sang Hyun Kim
Jung Il Noh
Su Myoung Lee
Mun Gyu Kim
Sang Ho Kim
Si Young Ok
Soon Im Kim
author_sort Sun Young Park
collection DOAJ
description BackgroundThis study was performed to evaluate the effectiveness of intravenous low dose ketamine for reducing the incidence and severity of postoperative sore throat (POST).MethodsThis was a prospective, randomized, double-blind clinical trial. The study population consisted of 70 patients between 20 and 70 years old who were classified as American Society of Anesthesiologists I-II and were scheduled for elective laparoscopic cholecystectomy. The patients were divided randomly into two groups. Patients in the ketamine group received an intravenous injection of 0.5 mg/kg of ketamine just before induction, followed by 10 µg/kg/min throughout the operation. Patients in the control group received intravenous saline instead of ketamine. The patients were interviewed 1, 6, and 24 h after the operation. The incidence and severity of POST were recorded.ResultsNo significant differences in the incidence and severity of POST during the 24 h after the operation were found between the two groups (21/31 in the ketamine group vs. 26/34 in the control group, P = 0.398).ConclusionsIntravenous injection of low dose ketamine was not effective for reducing POST.
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spelling doaj.art-4aa96899d31b47469ac701fc24e1b1072022-12-21T21:33:56ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632010-07-01591222610.4097/kjae.2010.59.1.226954The effect of intravenous low dose ketamine for reducing postoperative sore throatSun Young Park0Sang Hyun Kim1Jung Il Noh2Su Myoung Lee3Mun Gyu Kim4Sang Ho Kim5Si Young Ok6Soon Im Kim7Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Bucheon, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.BackgroundThis study was performed to evaluate the effectiveness of intravenous low dose ketamine for reducing the incidence and severity of postoperative sore throat (POST).MethodsThis was a prospective, randomized, double-blind clinical trial. The study population consisted of 70 patients between 20 and 70 years old who were classified as American Society of Anesthesiologists I-II and were scheduled for elective laparoscopic cholecystectomy. The patients were divided randomly into two groups. Patients in the ketamine group received an intravenous injection of 0.5 mg/kg of ketamine just before induction, followed by 10 µg/kg/min throughout the operation. Patients in the control group received intravenous saline instead of ketamine. The patients were interviewed 1, 6, and 24 h after the operation. The incidence and severity of POST were recorded.ResultsNo significant differences in the incidence and severity of POST during the 24 h after the operation were found between the two groups (21/31 in the ketamine group vs. 26/34 in the control group, P = 0.398).ConclusionsIntravenous injection of low dose ketamine was not effective for reducing POST.http://ekja.org/upload/pdf/kjae-59-22.pdfcomplicationsintubationketamine
spellingShingle Sun Young Park
Sang Hyun Kim
Jung Il Noh
Su Myoung Lee
Mun Gyu Kim
Sang Ho Kim
Si Young Ok
Soon Im Kim
The effect of intravenous low dose ketamine for reducing postoperative sore throat
Korean Journal of Anesthesiology
complications
intubation
ketamine
title The effect of intravenous low dose ketamine for reducing postoperative sore throat
title_full The effect of intravenous low dose ketamine for reducing postoperative sore throat
title_fullStr The effect of intravenous low dose ketamine for reducing postoperative sore throat
title_full_unstemmed The effect of intravenous low dose ketamine for reducing postoperative sore throat
title_short The effect of intravenous low dose ketamine for reducing postoperative sore throat
title_sort effect of intravenous low dose ketamine for reducing postoperative sore throat
topic complications
intubation
ketamine
url http://ekja.org/upload/pdf/kjae-59-22.pdf
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