Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service
Abstract Background Music therapy has been shown to be effective for multiple clinical endpoints associated with substance use disorder such as craving reduction, emotion regulation, depression, and anxiety, but there are a lack of studies investigating those effects in UK Community Substance Misuse...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-05-01
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| Series: | Addiction Science & Clinical Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13722-023-00385-y |
| _version_ | 1797817833720119296 |
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| author | Jörg Fachner Clemens Maidhof Daniel Murtagh Devon De Silva Filippo Pasqualitto Paul Fernie Francesca Panin Andrew Michell Leonardo Muller-Rodriguez Helen Odell-Miller |
| author_facet | Jörg Fachner Clemens Maidhof Daniel Murtagh Devon De Silva Filippo Pasqualitto Paul Fernie Francesca Panin Andrew Michell Leonardo Muller-Rodriguez Helen Odell-Miller |
| author_sort | Jörg Fachner |
| collection | DOAJ |
| description | Abstract Background Music therapy has been shown to be effective for multiple clinical endpoints associated with substance use disorder such as craving reduction, emotion regulation, depression, and anxiety, but there are a lack of studies investigating those effects in UK Community Substance Misuse Treatment Services (CSMTSs). Furthermore, there is a demand for identifying music therapy mechanisms of change and related brain processes for substance use disorder treatment. The present study aims to evaluate the feasibility and acceptability of music therapy and a pre-test, post-test, and in-session measurement battery in a CSMTS. Methods Fifteen participants, from a community service based in London, will take part in a mixed-methods non-blind randomized-controlled trial. Ten participants will receive six-weekly sessions of music therapy in addition to the standard treatment offered by the CSMTS—five of them will receive individual music therapy and five of them will receive group music therapy—while a further five participants will act as a control group receiving standard treatment only. Satisfaction and acceptability will be evaluated in focus groups with service users and staff members following the final treatment session. Moreover, attendance and completion rates will be monitored throughout the intervention. Subjective and behavioral indexes will be assessed before and after the interventions to explore the effects of music therapy on craving, substance use, symptoms of depression and anxiety, inhibitory control, and will be correlated with associated neurophysiological signatures. In-session analysis of two individual music therapy sessions will serve to explore how music and emotion are processed in the brain within the therapy. The data collected at each step will be included in an intention-to-treat analysis basis. Discussion This study will provide a first report on the feasibility of music therapy as an intervention for participants with substance use disorder engaged within a community service. It will also provide valuable information regarding the implementation of a multifaceted methodology that includes neurophysiological, questionnaire-based, and behavioral assessments in this cohort. Notwithstanding the limitation of a small sample size, the present study will provide novel preliminary data regarding neurophysiological outcomes in participants with substance use disorder that received music therapy. Trial Registration: ClinicalTrails.gov, NCT0518061, Registered 6 January 2022, https://clinicaltrials.gov/ct2/show/NCT05180617 |
| first_indexed | 2024-03-13T08:59:16Z |
| format | Article |
| id | doaj.art-4aaa6636ecdb4c1483c89578039338fd |
| institution | Directory Open Access Journal |
| issn | 1940-0640 |
| language | English |
| last_indexed | 2024-03-13T08:59:16Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Addiction Science & Clinical Practice |
| spelling | doaj.art-4aaa6636ecdb4c1483c89578039338fd2023-05-28T11:24:13ZengBMCAddiction Science & Clinical Practice1940-06402023-05-0118111510.1186/s13722-023-00385-yMusic therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment ServiceJörg Fachner0Clemens Maidhof1Daniel Murtagh2Devon De Silva3Filippo Pasqualitto4Paul Fernie5Francesca Panin6Andrew Michell7Leonardo Muller-Rodriguez8Helen Odell-Miller9Cambridge Institute for Music Therapy Research, Anglia Ruskin UniversityCambridge Institute for Music Therapy Research, Anglia Ruskin UniversityInnovation & Research Unit, Westminster Drug Project (WDP)Innovation & Research Unit, Westminster Drug Project (WDP)Cambridge Institute for Music Therapy Research, Anglia Ruskin UniversityCambridge Institute for Music Therapy Research, Anglia Ruskin UniversitySchool of Life Sciences, Faculty of Science and Engineering, Anglia Ruskin UniversityClinical Neurophysiology, Addenbrooke’s HospitalCambridge Institute for Music Therapy Research, Anglia Ruskin UniversityCambridge Institute for Music Therapy Research, Anglia Ruskin UniversityAbstract Background Music therapy has been shown to be effective for multiple clinical endpoints associated with substance use disorder such as craving reduction, emotion regulation, depression, and anxiety, but there are a lack of studies investigating those effects in UK Community Substance Misuse Treatment Services (CSMTSs). Furthermore, there is a demand for identifying music therapy mechanisms of change and related brain processes for substance use disorder treatment. The present study aims to evaluate the feasibility and acceptability of music therapy and a pre-test, post-test, and in-session measurement battery in a CSMTS. Methods Fifteen participants, from a community service based in London, will take part in a mixed-methods non-blind randomized-controlled trial. Ten participants will receive six-weekly sessions of music therapy in addition to the standard treatment offered by the CSMTS—five of them will receive individual music therapy and five of them will receive group music therapy—while a further five participants will act as a control group receiving standard treatment only. Satisfaction and acceptability will be evaluated in focus groups with service users and staff members following the final treatment session. Moreover, attendance and completion rates will be monitored throughout the intervention. Subjective and behavioral indexes will be assessed before and after the interventions to explore the effects of music therapy on craving, substance use, symptoms of depression and anxiety, inhibitory control, and will be correlated with associated neurophysiological signatures. In-session analysis of two individual music therapy sessions will serve to explore how music and emotion are processed in the brain within the therapy. The data collected at each step will be included in an intention-to-treat analysis basis. Discussion This study will provide a first report on the feasibility of music therapy as an intervention for participants with substance use disorder engaged within a community service. It will also provide valuable information regarding the implementation of a multifaceted methodology that includes neurophysiological, questionnaire-based, and behavioral assessments in this cohort. Notwithstanding the limitation of a small sample size, the present study will provide novel preliminary data regarding neurophysiological outcomes in participants with substance use disorder that received music therapy. Trial Registration: ClinicalTrails.gov, NCT0518061, Registered 6 January 2022, https://clinicaltrials.gov/ct2/show/NCT05180617https://doi.org/10.1186/s13722-023-00385-ySubstance use disorderMusic therapyCommunity treatment serviceFeasibilityRandomized controlled trialMental health |
| spellingShingle | Jörg Fachner Clemens Maidhof Daniel Murtagh Devon De Silva Filippo Pasqualitto Paul Fernie Francesca Panin Andrew Michell Leonardo Muller-Rodriguez Helen Odell-Miller Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service Addiction Science & Clinical Practice Substance use disorder Music therapy Community treatment service Feasibility Randomized controlled trial Mental health |
| title | Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service |
| title_full | Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service |
| title_fullStr | Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service |
| title_full_unstemmed | Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service |
| title_short | Music therapy, neural processing, and craving reduction: an RCT protocol for a mixed methods feasibility study in a Community Substance Misuse Treatment Service |
| title_sort | music therapy neural processing and craving reduction an rct protocol for a mixed methods feasibility study in a community substance misuse treatment service |
| topic | Substance use disorder Music therapy Community treatment service Feasibility Randomized controlled trial Mental health |
| url | https://doi.org/10.1186/s13722-023-00385-y |
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