Molecular Imaging and Preclinical Studies of Radiolabeled Long-Term RGD Peptides in U-87 MG Tumor-Bearing Mice

Molecular Imaging and Preclinical Studies of Radiolabeled Long-Term RGD Peptides in U-87 MG Tumor-Bearing Mice

The Arg–Gly–Asp (RGD) peptide shows a high affinity for α<sub>v</sub>β<sub>3</sub> integrin, which is overexpressed in new tumor blood vessels and many types of tumor cells. The radiolabeled RGD peptide has been studied for cancer imaging and radionuclide therapy. We have dev...

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Bibliographic Details
Main Authors: Wei-Lin Lo, Shih-Wei Lo, Su-Jung Chen, Ming-Wei Chen, Yuan-Ruei Huang, Liang-Cheng Chen, Chih-Hsien Chang, Ming-Hsin Li
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
<sup>111</sup>In-DOTA-EB-cRGDfK
indium-111
nanoSPECT/CT
pharmacokinetics
Online Access:https://www.mdpi.com/1422-0067/22/11/5459

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