Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population
Previous studies examining the association between kidney stone disease (KSD) and arterial stiffness have been limited. Both age and gender have been found to have an impact on KSD, but their influence on the relationship between KSD and increased arterial stiffness is unclear. This study included 6...
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MDPI AG
2020-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/6/1693 |
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| author | Zih-Jie Sun Hsuan-Jung Hsiao Hsiang-Ju Cheng Chieh-Ying Chou Feng-Hwa Lu Yi-Ching Yang Jin-Shang Wu Chih-Jen Chang |
| author_facet | Zih-Jie Sun Hsuan-Jung Hsiao Hsiang-Ju Cheng Chieh-Ying Chou Feng-Hwa Lu Yi-Ching Yang Jin-Shang Wu Chih-Jen Chang |
| author_sort | Zih-Jie Sun |
| collection | DOAJ |
| description | Previous studies examining the association between kidney stone disease (KSD) and arterial stiffness have been limited. Both age and gender have been found to have an impact on KSD, but their influence on the relationship between KSD and increased arterial stiffness is unclear. This study included 6694 subjects from October 2006 to August 2009. The diagnosis of kidney stone was based on the results of ultrasonographic examination. Increased arterial stiffness was defined as right-sided brachial-ankle pulse wave velocity (baPWV) ≥ 14 m/s. Associations between KSD and increased arterial stiffness were analyzed using multiple logistic regression models. KSD was positively related to increased arterial stiffness in both male and female groups (males: odds ratio [OR], 1.306; 95% confidence interval [CI], 1.035–1.649; females: OR, 1.585; 95% CI, 1.038–2.419) after adjusting for confounding factors. Subgroup analysis by age group (<50 and ≥50 years) showed a significant positive relationship only in the groups ≥ 50 years for both genders (males: OR, 1.546; 95% CI, 1.111–2.151; females: OR, 1.783; 95% CI, 1.042–3.054), but not in the groups < 50 years. In conclusion, KSD is associated with a higher risk of increased arterial stiffness in individuals aged ≥ 50 years, but not in those aged < 50 years for both genders. |
| first_indexed | 2024-03-10T19:25:50Z |
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| id | doaj.art-4ab0993bafd84adbb6391d88ce1ac695 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T19:25:50Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-4ab0993bafd84adbb6391d88ce1ac6952023-11-20T02:34:49ZengMDPI AGJournal of Clinical Medicine2077-03832020-06-0196169310.3390/jcm9061693Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese PopulationZih-Jie Sun0Hsuan-Jung Hsiao1Hsiang-Ju Cheng2Chieh-Ying Chou3Feng-Hwa Lu4Yi-Ching Yang5Jin-Shang Wu6Chih-Jen Chang7Department of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 70403, TaiwanPrevious studies examining the association between kidney stone disease (KSD) and arterial stiffness have been limited. Both age and gender have been found to have an impact on KSD, but their influence on the relationship between KSD and increased arterial stiffness is unclear. This study included 6694 subjects from October 2006 to August 2009. The diagnosis of kidney stone was based on the results of ultrasonographic examination. Increased arterial stiffness was defined as right-sided brachial-ankle pulse wave velocity (baPWV) ≥ 14 m/s. Associations between KSD and increased arterial stiffness were analyzed using multiple logistic regression models. KSD was positively related to increased arterial stiffness in both male and female groups (males: odds ratio [OR], 1.306; 95% confidence interval [CI], 1.035–1.649; females: OR, 1.585; 95% CI, 1.038–2.419) after adjusting for confounding factors. Subgroup analysis by age group (<50 and ≥50 years) showed a significant positive relationship only in the groups ≥ 50 years for both genders (males: OR, 1.546; 95% CI, 1.111–2.151; females: OR, 1.783; 95% CI, 1.042–3.054), but not in the groups < 50 years. In conclusion, KSD is associated with a higher risk of increased arterial stiffness in individuals aged ≥ 50 years, but not in those aged < 50 years for both genders.https://www.mdpi.com/2077-0383/9/6/1693kidney stonearterial stiffnesspulse wave velocityagegender |
| spellingShingle | Zih-Jie Sun Hsuan-Jung Hsiao Hsiang-Ju Cheng Chieh-Ying Chou Feng-Hwa Lu Yi-Ching Yang Jin-Shang Wu Chih-Jen Chang Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population Journal of Clinical Medicine kidney stone arterial stiffness pulse wave velocity age gender |
| title | Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population |
| title_full | Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population |
| title_fullStr | Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population |
| title_full_unstemmed | Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population |
| title_short | Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population |
| title_sort | relationship between kidney stone disease and arterial stiffness in a taiwanese population |
| topic | kidney stone arterial stiffness pulse wave velocity age gender |
| url | https://www.mdpi.com/2077-0383/9/6/1693 |
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