NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia

NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia

The immune system is important for elimination of residual leukemic cells during acute myeloid leukemia (AML) therapy. Anti-leukemia immune response can be inhibited by various mechanisms leading to immune evasion and disease relapse. Selected markers of immune escape were analyzed on AML cells from...

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Bibliographic Details
Main Authors: Kateřina Kuželová, Barbora Brodská, Jana Marková, Martina Petráčková, Johannes Schetelig, Šárka Ransdorfová, Zdenka Gašová, Cyril Šálek
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
AML
immunophenotype
NPM1
DNMT3A
TIM-3
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2073050

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