P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION

Objectives: In recent years, many studies emphasized the role of arterial rigidity in the development of cardiovascular diseases. Pulse pressure in an easy-obtained, reproducible marker of arterial stiffness and an independent cardiovascular risk factor. On the other hand it was observed that sodium...

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Main Authors: Adam Bednarski*, Katarzyna Stolarz-Skrzypek, Grzegorz Kielbasa, Agata Franczyk, Malgorzata Kloch-Badelek, Kalina Kawecka-Jaszcz, Danuta Czarnecka
Format: Article
Language:English
Published: BMC 2015-11-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930554/view
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author Adam Bednarski*
Katarzyna Stolarz-Skrzypek
Grzegorz Kielbasa
Agata Franczyk
Malgorzata Kloch-Badelek
Kalina Kawecka-Jaszcz
Danuta Czarnecka
author_facet Adam Bednarski*
Katarzyna Stolarz-Skrzypek
Grzegorz Kielbasa
Agata Franczyk
Malgorzata Kloch-Badelek
Kalina Kawecka-Jaszcz
Danuta Czarnecka
author_sort Adam Bednarski*
collection DOAJ
description Objectives: In recent years, many studies emphasized the role of arterial rigidity in the development of cardiovascular diseases. Pulse pressure in an easy-obtained, reproducible marker of arterial stiffness and an independent cardiovascular risk factor. On the other hand it was observed that sodium restriction could improve large elastic artery compliance. The aim of the study was to investigate the relation between salt intake and pulse pressure in high salt intake population. Methods: The study group included 303 subjects recruited from the general population of Southern Poland. Ambulatory blood pressure (ABP) monitors (SpaceLabs 90207) were programmed to obtain measurements each 15 min. during the day and each 30 min. nighttime. Based on the ABP data, we calculated pulse pressure (PP) over 24h, daytime and nighttime. Sodium intake was assessed based on 24h urinary sodium excretion. Database management and statistical analysis were performed with SAS software. Results: The study group included 136 men and 167 women, with 165 hypertensive individuals, 105 of them on antihypertensive treatment, mean age = 47.1 ± 15.7 yrs. While adjusting for age, sex, body mass index, 24h blood pressure, antihypertensive treatment, and life style, we observed positive relation between sodium intake and 24h PP ([beta±SE]: 0.016 ± 0.006, p = 0.0075), daytime PP ([beta±SE]: 0.011 ± 0.005, p = 0.029) and non-significant trend regarding nighttime PP ([beta±SE]: 0.009 ± 0.005, p = 0.094). Conclusion: In our high salt intake population, sodium intake was positively related to calculated pulse pressure over 24-hour and daytime.
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spelling doaj.art-4ab2a2796154482395dd2d02ad8958252022-12-22T03:25:05ZengBMCArtery Research1876-44012015-11-011210.1016/j.artres.2015.10.202P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATIONAdam Bednarski*Katarzyna Stolarz-SkrzypekGrzegorz KielbasaAgata FranczykMalgorzata Kloch-BadelekKalina Kawecka-JaszczDanuta CzarneckaObjectives: In recent years, many studies emphasized the role of arterial rigidity in the development of cardiovascular diseases. Pulse pressure in an easy-obtained, reproducible marker of arterial stiffness and an independent cardiovascular risk factor. On the other hand it was observed that sodium restriction could improve large elastic artery compliance. The aim of the study was to investigate the relation between salt intake and pulse pressure in high salt intake population. Methods: The study group included 303 subjects recruited from the general population of Southern Poland. Ambulatory blood pressure (ABP) monitors (SpaceLabs 90207) were programmed to obtain measurements each 15 min. during the day and each 30 min. nighttime. Based on the ABP data, we calculated pulse pressure (PP) over 24h, daytime and nighttime. Sodium intake was assessed based on 24h urinary sodium excretion. Database management and statistical analysis were performed with SAS software. Results: The study group included 136 men and 167 women, with 165 hypertensive individuals, 105 of them on antihypertensive treatment, mean age = 47.1 ± 15.7 yrs. While adjusting for age, sex, body mass index, 24h blood pressure, antihypertensive treatment, and life style, we observed positive relation between sodium intake and 24h PP ([beta±SE]: 0.016 ± 0.006, p = 0.0075), daytime PP ([beta±SE]: 0.011 ± 0.005, p = 0.029) and non-significant trend regarding nighttime PP ([beta±SE]: 0.009 ± 0.005, p = 0.094). Conclusion: In our high salt intake population, sodium intake was positively related to calculated pulse pressure over 24-hour and daytime.https://www.atlantis-press.com/article/125930554/view
spellingShingle Adam Bednarski*
Katarzyna Stolarz-Skrzypek
Grzegorz Kielbasa
Agata Franczyk
Malgorzata Kloch-Badelek
Kalina Kawecka-Jaszcz
Danuta Czarnecka
P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
Artery Research
title P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
title_full P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
title_fullStr P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
title_full_unstemmed P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
title_short P1.10 PULSE PRESSURE IN RELATION TO 24-HOUR URINARY SODIUM EXCRETION IN A SAMPLE OF HIGH-SALT INTAKE POPULATION
title_sort p1 10 pulse pressure in relation to 24 hour urinary sodium excretion in a sample of high salt intake population
url https://www.atlantis-press.com/article/125930554/view
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