Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disease characterized by the progressive degeneration of motor neurons. One of the key pathogenic factors implicated in ALS is TDP-43 (TAR DNA-binding protein 43), an RNA-binding protein encoded by the TARDBP gene. Under norma...
| Autori principali: | , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Frontiers Media S.A.
2025-02-01
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| Serie: | Frontiers in Molecular Medicine |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fmmed.2025.1530719/full |