Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings
Objective: Image-guided breast biopsy is commonly used for diagnosis of breast lesions. Breast ultrasound (US), which is also used for screening purposes, is an important tool to guide biopsies. In this study, we evaluated the radiologic-histopathologic correlation in patients who underwent US-guide...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-08-01
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| Series: | Cam & Sakura Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=csmedj&un=CSM-48658 |
| _version_ | 1827767289437487104 |
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| author | Handan Eren Tuce Soylemez Akkurt Hazal Izol Ozmen Mehmet Ali Nazli Ebru Sen Soykan Arikan Burcin Pehlivanoglu |
| author_facet | Handan Eren Tuce Soylemez Akkurt Hazal Izol Ozmen Mehmet Ali Nazli Ebru Sen Soykan Arikan Burcin Pehlivanoglu |
| author_sort | Handan Eren |
| collection | DOAJ |
| description | Objective: Image-guided breast biopsy is commonly used for diagnosis of breast lesions. Breast ultrasound (US), which is also used for screening purposes, is an important tool to guide biopsies. In this study, we evaluated the radiologic-histopathologic correlation in patients who underwent US-guided breast biopsy.
Material and Methods: A total of 126 biopsies from 116 consecutive cases were included. Patients' US and histopathological findings were retrospectively reviewed.
Results: All patients were female. Median age was 44+-12 (range; 16-66 years old). Two patients (2%) had bilateral, 8 (7%) had multifocal lesions. Breast Imaging Reporting and Data System (BI-RADS) was used for 115 lesions (91%). Three cases (2%) were BI-RADS 2, 27% (n=34) BI-RADS 3, 35% (n=44) BI-RADS 4, 25% (n=32) BI-RADS 5 and 2% (n=2) BI-RADS 6. Eight biopsies composed of normal breast tissue, which had been scored as BI-RADS 3 or 4, were considered inadequate. More than one-third (37%; n=47) were malignant as 28% (n=35) were consistent with fibroepithelial lesions and 11% (n=14) with inflammatory lesions. Major radiologic-histopathologic discordance was observed in only 2 cases, while there was minor discordance in 14. Ten of the 14 cases (11%) with minor discordance were BI-RADS 4 lesions and minor discordance was more common for benign lesions (p=0.013).
Conclusion: Our findings demonstrate a high radiologic-histopathologic correlation rate in US-guided breast biopsy samples. We observed the highest discordance in BI-RADS 4 lesions, suggesting that histopathological verification is necessary in patients with BI-RADS 4 lesions to exclude malignancy. |
| first_indexed | 2024-03-11T11:56:39Z |
| format | Article |
| id | doaj.art-4ab80939c1974c6f826f9576be8f3bf6 |
| institution | Directory Open Access Journal |
| issn | 2791-8823 |
| language | English |
| last_indexed | 2024-03-11T11:56:39Z |
| publishDate | 2022-08-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Cam & Sakura Medical Journal |
| spelling | doaj.art-4ab80939c1974c6f826f9576be8f3bf62023-11-08T13:05:28ZengGalenos Publishing HouseCam & Sakura Medical Journal2791-88232022-08-0122707410.4274/csmedj.galenos.2022.2021-12-5CSM-48658Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic FindingsHandan Eren0Tuce Soylemez Akkurt1Hazal Izol Ozmen2Mehmet Ali Nazli3Ebru Sen4Soykan Arikan5Burcin Pehlivanoglu6University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of Pathology, İstanbul, TurkeyUniversity of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of Pathology, İstanbul, TurkeyUniversity of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of Pathology, İstanbul, TurkeyUniversity of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of Radiology, İstanbul, TurkeyUniversity of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of General Surgery, İstanbul, TurkeyUniversity of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Department of General Surgery, İstanbul, TurkeyDokuz Eylul University Hospital, Department of Pathology, Izmir, TurkeyObjective: Image-guided breast biopsy is commonly used for diagnosis of breast lesions. Breast ultrasound (US), which is also used for screening purposes, is an important tool to guide biopsies. In this study, we evaluated the radiologic-histopathologic correlation in patients who underwent US-guided breast biopsy. Material and Methods: A total of 126 biopsies from 116 consecutive cases were included. Patients' US and histopathological findings were retrospectively reviewed. Results: All patients were female. Median age was 44+-12 (range; 16-66 years old). Two patients (2%) had bilateral, 8 (7%) had multifocal lesions. Breast Imaging Reporting and Data System (BI-RADS) was used for 115 lesions (91%). Three cases (2%) were BI-RADS 2, 27% (n=34) BI-RADS 3, 35% (n=44) BI-RADS 4, 25% (n=32) BI-RADS 5 and 2% (n=2) BI-RADS 6. Eight biopsies composed of normal breast tissue, which had been scored as BI-RADS 3 or 4, were considered inadequate. More than one-third (37%; n=47) were malignant as 28% (n=35) were consistent with fibroepithelial lesions and 11% (n=14) with inflammatory lesions. Major radiologic-histopathologic discordance was observed in only 2 cases, while there was minor discordance in 14. Ten of the 14 cases (11%) with minor discordance were BI-RADS 4 lesions and minor discordance was more common for benign lesions (p=0.013). Conclusion: Our findings demonstrate a high radiologic-histopathologic correlation rate in US-guided breast biopsy samples. We observed the highest discordance in BI-RADS 4 lesions, suggesting that histopathological verification is necessary in patients with BI-RADS 4 lesions to exclude malignancy.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=csmedj&un=CSM-48658biopsybreasthistopathologyradiologyultrasonography |
| spellingShingle | Handan Eren Tuce Soylemez Akkurt Hazal Izol Ozmen Mehmet Ali Nazli Ebru Sen Soykan Arikan Burcin Pehlivanoglu Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings Cam & Sakura Medical Journal biopsy breast histopathology radiology ultrasonography |
| title | Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings |
| title_full | Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings |
| title_fullStr | Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings |
| title_full_unstemmed | Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings |
| title_short | Ultrasound-guided Breast Biopsy: Evaluation of the Correlation Between Radiologic and Histopathologic Findings |
| title_sort | ultrasound guided breast biopsy evaluation of the correlation between radiologic and histopathologic findings |
| topic | biopsy breast histopathology radiology ultrasonography |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=csmedj&un=CSM-48658 |
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