Large and stable genome edits at the sorghum alpha kafirin locus result in changes in chromatin accessibility and globally increased expression of genes encoding lysine enrichment

Large and stable genome edits at the sorghum alpha kafirin locus result in changes in chromatin accessibility and globally increased expression of genes encoding lysine enrichment

IntroductionSorghum is a resilient and widely cultivated grain crop used for feed and food. However, it’s grain is deficient in lysine, an essential amino acid. This is due to the primary seed storage proteins, the alpha-kafirins, lacking lysine. It has been observed that reductions in alpha-kafirin...

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Bibliographic Details
Main Authors: J. Preston Hurst, Abou Yobi, Aixia Li, Shirley Sato, Thomas E. Clemente, Ruthie Angelovici, David R. Holding
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Plant Science
Subjects:
CRISPR/Cas9
sorghum
ATACseq
RNAseq
seed protein
grain quality
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2023.1116886/full

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