Histone methylation and DNA methylation: a missed pas de deux in invertebrates?

Several Authors have reported that histone methylation interacts with DNA methylation creating aself-propagating epigenetic cycle for long-term transcriptional repression of methylated genomecompartments. This phenomenon, observed in plant and vertebrate genomes, does not appear to holdtrue in inver...

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Bibliographic Details
Main Authors: M Mandrioli, F Borsatti
Format: Article
Language:English
Published: University of Modena and Reggio Emilia 2005-12-01
Series:Invertebrate Survival Journal
Subjects:
Online Access:http://www.isj.unimo.it/articoli/ISJ110.pdf
Description
Summary:Several Authors have reported that histone methylation interacts with DNA methylation creating aself-propagating epigenetic cycle for long-term transcriptional repression of methylated genomecompartments. This phenomenon, observed in plant and vertebrate genomes, does not appear to holdtrue in invertebrates. In particular, both structural and functional evidences suggest that, ininvertebrates, DNA methylation and histone methylation do not interact, thus inhibiting the intimate pasde deux observed in other eukaryotes.
ISSN:1824-307X