Circulating maternal chimeric cells have an impact on the outcome of biliary atresia

Circulating maternal chimeric cells have an impact on the outcome of biliary atresia

IntroductionWe aimed to quantify the DNA of maternal chimeric (MC) cells in the peripheral blood of the BA patients and investigated the impact on the outcome.MethodsPatients with progressive jaundice because of no bile flow, which necessitated liver transplantation, or who showed inadequate bile fl...

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Bibliographic Details
Main Authors: Ryuta Masuya, Toshihiro Muraji, Sami B. Kanaan, Toshio Harumatsu, Mitsuru Muto, Miki Toma, Toshihiro Yanai, Anne M. Stevens, J. Lee Nelson, Kazuhiko Nakame, Atsushi Nanashima, Satoshi Ieiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pediatrics
Subjects:
biliary atresia
maternal microchimerism
qPCR
prognosis
GVHD
autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.1007927/full

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