Is intraperitoneal chemotherapy beneficial in pancreatic cancer?
The role of intraperitoneal chemotherapy has been widely investigated in locally advanced malignancies which serosal involvement as well as in cases in which disseminated peritoneal nodules are present. However, its benefits have been widely contested by the higher rates of perioperative complicatio...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2022-06-01
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| Series: | Romanian Journal of Medical Practice |
| Subjects: | |
| Online Access: | https://rjmp.com.ro/articles/2022.2/RJMP_2022_2_Art-09.pdf |
| _version_ | 1827952038116327424 |
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| author | Irina Balescu Nicolae Bacalbasa Claudia Stoica Lucian Pop Valentin Varlas Cristina Martac Andrei Voichitoiu Tarig Massawi |
| author_facet | Irina Balescu Nicolae Bacalbasa Claudia Stoica Lucian Pop Valentin Varlas Cristina Martac Andrei Voichitoiu Tarig Massawi |
| author_sort | Irina Balescu |
| collection | DOAJ |
| description | The role of intraperitoneal chemotherapy has been widely investigated in locally advanced malignancies which serosal involvement as well as in cases in which disseminated peritoneal nodules are present. However, its benefits have been widely contested by the higher rates of perioperative complications and therefore, the
guidelines did not include it as part of standard therapy. Meanwhile, the better control of the intraperitoneal spread which has been demonstrated in certain cases enabled surgeons to propose performing intraperitoneal chemotherapy in particularly aggressive malignancies such as pancreatic cancer. The aim of the current paper is to discuss about the efficacy and the preliminary results of intraperitoneal chemotherapy in pancreatic cancer. |
| first_indexed | 2024-04-09T13:51:29Z |
| format | Article |
| id | doaj.art-4ad5b92402734eacb6ed8710616ee705 |
| institution | Directory Open Access Journal |
| issn | 1842-8258 2069-6108 |
| language | English |
| last_indexed | 2024-04-09T13:51:29Z |
| publishDate | 2022-06-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Medical Practice |
| spelling | doaj.art-4ad5b92402734eacb6ed8710616ee7052023-05-08T15:18:28ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082022-06-0117210210410.37897/RJMP.2022.2.9Is intraperitoneal chemotherapy beneficial in pancreatic cancer? Irina Balescu0Nicolae Bacalbasa1Claudia Stoica2Lucian Pop3Valentin Varlas4Cristina Martac5Andrei Voichitoiu6Tarig Massawi7Department of Visceral Surgery, Ponderas Academic Hospital, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Visceral Surgery, Center of Excellence in Translational Medicine, Fundeni Clinical Institute, Bucharest, RomaniaDepartment of Anatomy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Surgery, Ilfov County Emergency Hospital, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, ”Alessandrescu-Rusescu”National Institute of Mother and Child Care, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, Bucharest, RomaniaDepartment of Anesthesiology, Fundeni Clinical Institute, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Obstetrics and Gynecology, ”Alessandrescu-Rusescu”National Institute of Mother and Child Care, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, Ilfov County Emergency Hospital, Bucharest, RomaniaThe role of intraperitoneal chemotherapy has been widely investigated in locally advanced malignancies which serosal involvement as well as in cases in which disseminated peritoneal nodules are present. However, its benefits have been widely contested by the higher rates of perioperative complications and therefore, the guidelines did not include it as part of standard therapy. Meanwhile, the better control of the intraperitoneal spread which has been demonstrated in certain cases enabled surgeons to propose performing intraperitoneal chemotherapy in particularly aggressive malignancies such as pancreatic cancer. The aim of the current paper is to discuss about the efficacy and the preliminary results of intraperitoneal chemotherapy in pancreatic cancer.https://rjmp.com.ro/articles/2022.2/RJMP_2022_2_Art-09.pdfpancreatic cancerintraperitoneal chemotherapylocal controlsurvival |
| spellingShingle | Irina Balescu Nicolae Bacalbasa Claudia Stoica Lucian Pop Valentin Varlas Cristina Martac Andrei Voichitoiu Tarig Massawi Is intraperitoneal chemotherapy beneficial in pancreatic cancer? Romanian Journal of Medical Practice pancreatic cancer intraperitoneal chemotherapy local control survival |
| title | Is intraperitoneal chemotherapy beneficial in pancreatic cancer? |
| title_full | Is intraperitoneal chemotherapy beneficial in pancreatic cancer? |
| title_fullStr | Is intraperitoneal chemotherapy beneficial in pancreatic cancer? |
| title_full_unstemmed | Is intraperitoneal chemotherapy beneficial in pancreatic cancer? |
| title_short | Is intraperitoneal chemotherapy beneficial in pancreatic cancer? |
| title_sort | is intraperitoneal chemotherapy beneficial in pancreatic cancer |
| topic | pancreatic cancer intraperitoneal chemotherapy local control survival |
| url | https://rjmp.com.ro/articles/2022.2/RJMP_2022_2_Art-09.pdf |
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