Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment

Abstract The novel time‐limited combinations with the bcl‐2 inhibitor venetoclax can induce deep responses even in CLL cases with unusual and biologically aggressive presentations, like the skin masses of our patient.

Bibliographic Details
Main Authors: Maria Dimou, Theodoros Iliakis, Vasileios Paradalis, Aikaterini Bitsani, Marie‐Christine Kyrtsonis, Panayiotis Panayiotidis
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.4514
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author Maria Dimou
Theodoros Iliakis
Vasileios Paradalis
Aikaterini Bitsani
Marie‐Christine Kyrtsonis
Panayiotis Panayiotidis
author_facet Maria Dimou
Theodoros Iliakis
Vasileios Paradalis
Aikaterini Bitsani
Marie‐Christine Kyrtsonis
Panayiotis Panayiotidis
author_sort Maria Dimou
collection DOAJ
description Abstract The novel time‐limited combinations with the bcl‐2 inhibitor venetoclax can induce deep responses even in CLL cases with unusual and biologically aggressive presentations, like the skin masses of our patient.
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spelling doaj.art-4ad7baa08ff74c5fbbaccb6a3fdcd4722023-03-27T08:34:51ZengWileyClinical Case Reports2050-09042021-07-0197n/an/a10.1002/ccr3.4514Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatmentMaria Dimou0Theodoros Iliakis1Vasileios Paradalis2Aikaterini Bitsani3Marie‐Christine Kyrtsonis4Panayiotis Panayiotidis5First Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceFirst Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceFirst Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceFirst Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceFirst Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceFirst Department of Internal Medicine, Propaedeutic, Hematology Clinical Trial Unit Laiko General Hospital Athens GreeceAbstract The novel time‐limited combinations with the bcl‐2 inhibitor venetoclax can induce deep responses even in CLL cases with unusual and biologically aggressive presentations, like the skin masses of our patient.https://doi.org/10.1002/ccr3.4514CLL/SLLMRD negativityskin nodulestime‐limited treatmentvenetoclax
spellingShingle Maria Dimou
Theodoros Iliakis
Vasileios Paradalis
Aikaterini Bitsani
Marie‐Christine Kyrtsonis
Panayiotis Panayiotidis
Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
Clinical Case Reports
CLL/SLL
MRD negativity
skin nodules
time‐limited treatment
venetoclax
title Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
title_full Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
title_fullStr Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
title_full_unstemmed Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
title_short Complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time‐limited venetoclax/obinutuzumab treatment
title_sort complete eradication of chronic lymphocytic leukemia with unusual skin involvement of high mitotic index after time limited venetoclax obinutuzumab treatment
topic CLL/SLL
MRD negativity
skin nodules
time‐limited treatment
venetoclax
url https://doi.org/10.1002/ccr3.4514
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AT theodorosiliakis completeeradicationofchroniclymphocyticleukemiawithunusualskininvolvementofhighmitoticindexaftertimelimitedvenetoclaxobinutuzumabtreatment
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