Vitamin B12 induced acneiform eruption

A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin. 6 weeks after its initiation, the patient presented a sudden, extensive and monomorphic eruption of inflammatory papulo-pustules and nodules, affecting...

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Main Authors: Imane Bahbouhi, Maryem Aboudourib, Ouafa Hocar, Said Amal
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023033273
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author Imane Bahbouhi
Maryem Aboudourib
Ouafa Hocar
Said Amal
author_facet Imane Bahbouhi
Maryem Aboudourib
Ouafa Hocar
Said Amal
author_sort Imane Bahbouhi
collection DOAJ
description A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin. 6 weeks after its initiation, the patient presented a sudden, extensive and monomorphic eruption of inflammatory papulo-pustules and nodules, affecting the face, and the trunk. The eruption was pruritic, and comedones were also present, on the chest. The patient was diagnosed with vitamin B12-induced acneiform eruption. Levels of vitamin B12 were normalized. Hydroxocobalamin was therefore stopped and lymecycline was started, allowing a complete resolution of the lesions within 3 months. Drug intake, sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of extra-seborrheic areas are features that distinguish acneiform eruptions from acne vulgaris.
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spelling doaj.art-4ada52177ace495ba986b77ee8c86b8c2023-05-31T04:46:42ZengElsevierHeliyon2405-84402023-05-0195e16120Vitamin B12 induced acneiform eruptionImane Bahbouhi0Maryem Aboudourib1Ouafa Hocar2Said Amal3Corresponding author.; Department of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, MoroccoDepartment of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, MoroccoDepartment of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, MoroccoDepartment of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, MoroccoA 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin. 6 weeks after its initiation, the patient presented a sudden, extensive and monomorphic eruption of inflammatory papulo-pustules and nodules, affecting the face, and the trunk. The eruption was pruritic, and comedones were also present, on the chest. The patient was diagnosed with vitamin B12-induced acneiform eruption. Levels of vitamin B12 were normalized. Hydroxocobalamin was therefore stopped and lymecycline was started, allowing a complete resolution of the lesions within 3 months. Drug intake, sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of extra-seborrheic areas are features that distinguish acneiform eruptions from acne vulgaris.http://www.sciencedirect.com/science/article/pii/S2405844023033273Acneiform eruptionAcneVitamin B12
spellingShingle Imane Bahbouhi
Maryem Aboudourib
Ouafa Hocar
Said Amal
Vitamin B12 induced acneiform eruption
Heliyon
Acneiform eruption
Acne
Vitamin B12
title Vitamin B12 induced acneiform eruption
title_full Vitamin B12 induced acneiform eruption
title_fullStr Vitamin B12 induced acneiform eruption
title_full_unstemmed Vitamin B12 induced acneiform eruption
title_short Vitamin B12 induced acneiform eruption
title_sort vitamin b12 induced acneiform eruption
topic Acneiform eruption
Acne
Vitamin B12
url http://www.sciencedirect.com/science/article/pii/S2405844023033273
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AT maryemaboudourib vitaminb12inducedacneiformeruption
AT ouafahocar vitaminb12inducedacneiformeruption
AT saidamal vitaminb12inducedacneiformeruption