Neuroprotective Effects of Transferrin in Experimental Glaucoma Models

Neuroprotective Effects of Transferrin in Experimental Glaucoma Models

Iron is essential for retinal metabolism, but an excess of ferrous iron causes oxidative stress. In glaucomatous eyes, retinal ganglion cell (RGC) death has been associated with dysregulation of iron homeostasis. Transferrin (TF) is an endogenous iron transporter that controls ocular iron levels. In...

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Bibliographic Details
Main Authors: Jenny Youale, Karine Bigot, Bindu Kodati, Thara Jaworski, Yan Fan, Nana Yaa Nsiah, Nathaniel Pappenhagen, Denise M. Inman, Francine Behar-Cohen, Thierry Bordet, Emilie Picard
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
ferroptosis
glaucoma
iron
neuroprotection
ocular hypertension
RGC
Online Access:https://www.mdpi.com/1422-0067/23/21/12753

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