Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches

Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches

This study aimed to refine combined targeted approaches on well-characterized, low-passage tumor models. Upon in vivo xenografting in immunodeficient mice, three cell lines from locally advanced or metastatic HNSCC were established. Following quality control and basic characterization, drug response...

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Bibliographic Details
Main Authors: Nina Schoenwaelder, Mareike Krause, Thomas Freitag, Björn Schneider, Sarah Zonnur, Annette Zimpfer, Anne Sophie Becker, Inken Salewski, Daniel Fabian Strüder, Heiko Lemcke, Christina Grosse-Thie, Christian Junghanss, Claudia Maletzki
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
cisplatin sensitivity
migration
invasion
phenotype
molecular alterations
preclinical tumor models
Online Access:https://www.mdpi.com/2072-6694/14/10/2484

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https://www.mdpi.com/2072-6694/14/10/2484

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