Global Epidemiology of Lung Cancer
While lung cancer has been the leading cause of cancer-related deaths for many years in the United States, incidence and mortality statistics – among other measures – vary widely worldwide. The aim of this study was to review the evidence on lung cancer epidemiology, including data of international...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Ubiquity Press
2019-01-01
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| Series: | Annals of Global Health |
| Online Access: | https://annalsofglobalhealth.org/articles/2419 |
| _version_ | 1818901461325578240 |
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| author | Julie A. Barta Charles A. Powell Juan P. Wisnivesky |
| author_facet | Julie A. Barta Charles A. Powell Juan P. Wisnivesky |
| author_sort | Julie A. Barta |
| collection | DOAJ |
| description | While lung cancer has been the leading cause of cancer-related deaths for many years in the United States, incidence and mortality statistics – among other measures – vary widely worldwide. The aim of this study was to review the evidence on lung cancer epidemiology, including data of international scope with comparisons of economically, socially, and biologically different patient groups. In industrialized nations, evolving social and cultural smoking patterns have led to rising or plateauing rates of lung cancer in women, lagging the long-declining smoking and cancer incidence rates in men. In contrast, emerging economies vary widely in smoking practices and cancer incidence but commonly also harbor risks from environmental exposures, particularly widespread air pollution. Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. Furthermore, emergent evidence about the benefits of lung cancer screening has led to efforts to identify high-risk smokers and development of prediction tools. This review also includes a discussion on the epidemiologic characteristics of special groups including women and nonsmokers. Varying trends in smoking largely dictate international patterns in lung cancer incidence and mortality. With declining smoking rates in developed countries and knowledge gains made through molecular profiling of tumors, the emergence of new risk factors and disease features will lead to changes in the landscape of lung cancer epidemiology. |
| first_indexed | 2024-12-19T20:20:07Z |
| format | Article |
| id | doaj.art-4ae20ff1433848d5b7c6418b963f54bc |
| institution | Directory Open Access Journal |
| issn | 2214-9996 |
| language | English |
| last_indexed | 2024-12-19T20:20:07Z |
| publishDate | 2019-01-01 |
| publisher | Ubiquity Press |
| record_format | Article |
| series | Annals of Global Health |
| spelling | doaj.art-4ae20ff1433848d5b7c6418b963f54bc2022-12-21T20:07:02ZengUbiquity PressAnnals of Global Health2214-99962019-01-0185110.5334/aogh.24192268Global Epidemiology of Lung CancerJulie A. Barta0Charles A. Powell1Juan P. Wisnivesky2Division of Pulmonary and Critical Care Medicine, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PADivision of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NYDivision of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NYWhile lung cancer has been the leading cause of cancer-related deaths for many years in the United States, incidence and mortality statistics – among other measures – vary widely worldwide. The aim of this study was to review the evidence on lung cancer epidemiology, including data of international scope with comparisons of economically, socially, and biologically different patient groups. In industrialized nations, evolving social and cultural smoking patterns have led to rising or plateauing rates of lung cancer in women, lagging the long-declining smoking and cancer incidence rates in men. In contrast, emerging economies vary widely in smoking practices and cancer incidence but commonly also harbor risks from environmental exposures, particularly widespread air pollution. Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. Furthermore, emergent evidence about the benefits of lung cancer screening has led to efforts to identify high-risk smokers and development of prediction tools. This review also includes a discussion on the epidemiologic characteristics of special groups including women and nonsmokers. Varying trends in smoking largely dictate international patterns in lung cancer incidence and mortality. With declining smoking rates in developed countries and knowledge gains made through molecular profiling of tumors, the emergence of new risk factors and disease features will lead to changes in the landscape of lung cancer epidemiology.https://annalsofglobalhealth.org/articles/2419 |
| spellingShingle | Julie A. Barta Charles A. Powell Juan P. Wisnivesky Global Epidemiology of Lung Cancer Annals of Global Health |
| title | Global Epidemiology of Lung Cancer |
| title_full | Global Epidemiology of Lung Cancer |
| title_fullStr | Global Epidemiology of Lung Cancer |
| title_full_unstemmed | Global Epidemiology of Lung Cancer |
| title_short | Global Epidemiology of Lung Cancer |
| title_sort | global epidemiology of lung cancer |
| url | https://annalsofglobalhealth.org/articles/2419 |
| work_keys_str_mv | AT julieabarta globalepidemiologyoflungcancer AT charlesapowell globalepidemiologyoflungcancer AT juanpwisnivesky globalepidemiologyoflungcancer |