Relationship between perioperative oncological evaluation and recurrence using circulating tumor DNA with KRAS mutation in patients with colorectal cancer

Relationship between perioperative oncological evaluation and recurrence using circulating tumor DNA with KRAS mutation in patients with colorectal cancer

Abstract Background The detection of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) by liquid biopsy may have prognostic information. In this perioperative study, we evaluate if there is a relationship between mutant allele frequency (MAF) of Kirsten rat sarcoma viral oncogene homolog (KRA...

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Bibliographic Details
Main Authors: Takaomi Hayashi, Yoichiro Yoshida, Teppei Yamada, Keita Tanaka, Hideki Shimaoka, Ryuji Kajitani, Taro Munechika, Hideki Nagano, Yoshiko Matsumoto, Akira Komono, Ryohei Sakamoto, Naoya Aisu, Gumpei Yoshimatsu, Fumihiro Yoshimura, Suguru Hasegawa
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Cancer Medicine
Subjects:
circulating tumor DNA
colorectal cancer
digital PCR
KRAS
liquid biopsy
Online Access:https://doi.org/10.1002/cam4.4677

Internet

https://doi.org/10.1002/cam4.4677

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