Metabolic disorders in patients with vestibular migraine
Objective: to assess vitamin D deficiency and hyperhomocysteinemia along with psychoemotional status in patients with vestibular migraine.Material and methods. The neurovestibular examination of 23 patients was performed. All patients were diagnosed with vestibular migraine in accordance with the in...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2022-01-01
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| Series: | Эпилепсия и пароксизмальные состояния |
| Subjects: | |
| Online Access: | https://www.epilepsia.su/jour/article/view/750 |
| _version_ | 1797879368736833536 |
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| author | A. S. Bedenko L. M. Antonenko |
| author_facet | A. S. Bedenko L. M. Antonenko |
| author_sort | A. S. Bedenko |
| collection | DOAJ |
| description | Objective: to assess vitamin D deficiency and hyperhomocysteinemia along with psychoemotional status in patients with vestibular migraine.Material and methods. The neurovestibular examination of 23 patients was performed. All patients were diagnosed with vestibular migraine in accordance with the international criteria. The levels of 25-hydroxyvitamin D and homocysteine were assessed by enzyme-linked immunosorbent assay (ELISA). The effect of dizziness on everyday life was assessed according to the Dizziness Handicap Inventory (DHI). Psychoemotional status was investigated for all patients by using the following scales: Beck depression scale, Spilber–Hanin Scale, Toronto Alexithymia Scale (TAS-26).Results. The mean level of 25-hydroxyvitamin D was 23±15 ng/ml, homocysteine – 11±3.4 μmol/L. The mean levels of situational and personal anxiety were 48.8±9 and 50.4±10.8, respectively. A correlation analysis revealed a significant positive correlation for Beck's depression parameters and DHI score (Spearman's criterion value 0.64, p=0.0016).Conclusion. The data obtained evidence about a rather frequent detection of 25-hydroxyvitamin D insufficiency and deficit among patients with vestibular migraine that requires further evaluation, including expanding patients sample and/or comparison with other groups of patients. Of significance was to find an elevated level of anxiety and a correlation between the severity of dizziness (according to DHI score) and the level of depression (based on the Beck Scale). |
| first_indexed | 2024-04-10T02:46:39Z |
| format | Article |
| id | doaj.art-4aedefabb56d4cb2a9363f62fc0a2a36 |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:46:39Z |
| publishDate | 2022-01-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-4aedefabb56d4cb2a9363f62fc0a2a362023-03-13T07:44:18ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882022-01-0113435936610.17749/2077-8333/epi.par.con.2021.094562Metabolic disorders in patients with vestibular migraineA. S. Bedenko0L. M. Antonenko1Sechenov UniversitySechenov UniversityObjective: to assess vitamin D deficiency and hyperhomocysteinemia along with psychoemotional status in patients with vestibular migraine.Material and methods. The neurovestibular examination of 23 patients was performed. All patients were diagnosed with vestibular migraine in accordance with the international criteria. The levels of 25-hydroxyvitamin D and homocysteine were assessed by enzyme-linked immunosorbent assay (ELISA). The effect of dizziness on everyday life was assessed according to the Dizziness Handicap Inventory (DHI). Psychoemotional status was investigated for all patients by using the following scales: Beck depression scale, Spilber–Hanin Scale, Toronto Alexithymia Scale (TAS-26).Results. The mean level of 25-hydroxyvitamin D was 23±15 ng/ml, homocysteine – 11±3.4 μmol/L. The mean levels of situational and personal anxiety were 48.8±9 and 50.4±10.8, respectively. A correlation analysis revealed a significant positive correlation for Beck's depression parameters and DHI score (Spearman's criterion value 0.64, p=0.0016).Conclusion. The data obtained evidence about a rather frequent detection of 25-hydroxyvitamin D insufficiency and deficit among patients with vestibular migraine that requires further evaluation, including expanding patients sample and/or comparison with other groups of patients. Of significance was to find an elevated level of anxiety and a correlation between the severity of dizziness (according to DHI score) and the level of depression (based on the Beck Scale).https://www.epilepsia.su/jour/article/view/750spinning vertigovestibular migrainevitamin d insufficiencyhomocysteine |
| spellingShingle | A. S. Bedenko L. M. Antonenko Metabolic disorders in patients with vestibular migraine Эпилепсия и пароксизмальные состояния spinning vertigo vestibular migraine vitamin d insufficiency homocysteine |
| title | Metabolic disorders in patients with vestibular migraine |
| title_full | Metabolic disorders in patients with vestibular migraine |
| title_fullStr | Metabolic disorders in patients with vestibular migraine |
| title_full_unstemmed | Metabolic disorders in patients with vestibular migraine |
| title_short | Metabolic disorders in patients with vestibular migraine |
| title_sort | metabolic disorders in patients with vestibular migraine |
| topic | spinning vertigo vestibular migraine vitamin d insufficiency homocysteine |
| url | https://www.epilepsia.su/jour/article/view/750 |
| work_keys_str_mv | AT asbedenko metabolicdisordersinpatientswithvestibularmigraine AT lmantonenko metabolicdisordersinpatientswithvestibularmigraine |