The Underlying Biology and Therapeutic Vulnerabilities of Leptomeningeal Metastases in Adult Solid Cancers
Metastasis to the central nervous system occurs in approximately 20% of patients with advanced solid cancers such as lung cancer, breast cancer, and melanoma. While central nervous system metastases most commonly form in the brain parenchyma, metastatic cancer cells may also reside in the subarachno...
Main Authors: | Matthew Dankner, Stephanie Lam, Theresa Degenhard, Livia Garzia, Marie-Christine Guiot, Kevin Petrecca, Peter M. Siegel |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/4/732 |
Similar Items
-
Leptomeningeal Metastases in Melanoma Patients: An Update on and Future Perspectives for Diagnosis and Treatment
by: Julian Steininger, et al.
Published: (2023-07-01) -
Genomic alterations of cerebrospinal fluid cell-free DNA in leptomeningeal metastases of gastric cancer
by: Xin Chen, et al.
Published: (2023-05-01) -
Management of Brain and Leptomeningeal Metastases from Breast Cancer
by: Alessia Pellerino, et al.
Published: (2020-11-01) -
Long survival of a patient with leptomeningeal infiltration in breast cancer: A case report
by: Al-Bairmany Yaala Saady Raof
Published: (2024-04-01) -
HER2+ esophageal carcinoma leptomeningeal metastases treated with intrathecal trastuzumab regimen
by: Scott A Wu, et al.
Published: (2023-09-01)