White Clot Formation at Acetylcholine Testing

Coronary intraluminal white clot formation, apparently in response to acetylcholine testing, may explain a woman’s long-term history of daily chest pain and multiple myocardial infarctions. Acetylcholine testing reproduced chest pain and revealed luminal filling defects in multiple vessels; imaging...

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Main Authors: Paolo Angelini, MD, Maria T. Gamero, MD, Carlo Uribe, MD
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:JACC: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084921002345
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author Paolo Angelini, MD
Maria T. Gamero, MD
Carlo Uribe, MD
author_facet Paolo Angelini, MD
Maria T. Gamero, MD
Carlo Uribe, MD
author_sort Paolo Angelini, MD
collection DOAJ
description Coronary intraluminal white clot formation, apparently in response to acetylcholine testing, may explain a woman’s long-term history of daily chest pain and multiple myocardial infarctions. Acetylcholine testing reproduced chest pain and revealed luminal filling defects in multiple vessels; imaging showed fresh white platelet clots. Antiplatelet prasugrel has substantially suppressed her symptoms. (Level of Difficulty: Advanced.)
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spelling doaj.art-4af045e458384a579ee423fcb700be822022-12-21T19:24:41ZengElsevierJACC: Case Reports2666-08492021-05-0135801805White Clot Formation at Acetylcholine TestingPaolo Angelini, MD0Maria T. Gamero, MD1Carlo Uribe, MD2Department of Cardiology, Texas Heart Institute, Houston, Texas, USA; Address for correspondence: Dr. Paolo Angelini, Texas Heart Institute, 6624 Fannin Street, Suite 2780, Houston, Texas 77030, USA.Department of Internal Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USADepartment of Cardiology, Texas Heart Institute, Houston, Texas, USACoronary intraluminal white clot formation, apparently in response to acetylcholine testing, may explain a woman’s long-term history of daily chest pain and multiple myocardial infarctions. Acetylcholine testing reproduced chest pain and revealed luminal filling defects in multiple vessels; imaging showed fresh white platelet clots. Antiplatelet prasugrel has substantially suppressed her symptoms. (Level of Difficulty: Advanced.)http://www.sciencedirect.com/science/article/pii/S2666084921002345angina pectoriscoronary artery diseasecoronary vasospasmmyocardial infarctionplatelet aggregationplatelet aggregation inhibitors
spellingShingle Paolo Angelini, MD
Maria T. Gamero, MD
Carlo Uribe, MD
White Clot Formation at Acetylcholine Testing
JACC: Case Reports
angina pectoris
coronary artery disease
coronary vasospasm
myocardial infarction
platelet aggregation
platelet aggregation inhibitors
title White Clot Formation at Acetylcholine Testing
title_full White Clot Formation at Acetylcholine Testing
title_fullStr White Clot Formation at Acetylcholine Testing
title_full_unstemmed White Clot Formation at Acetylcholine Testing
title_short White Clot Formation at Acetylcholine Testing
title_sort white clot formation at acetylcholine testing
topic angina pectoris
coronary artery disease
coronary vasospasm
myocardial infarction
platelet aggregation
platelet aggregation inhibitors
url http://www.sciencedirect.com/science/article/pii/S2666084921002345
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AT mariatgameromd whiteclotformationatacetylcholinetesting
AT carlouribemd whiteclotformationatacetylcholinetesting