CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells

CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells

CCN1 and CCN2 are members of the CCN family and play essential roles in the regulation of multiple female reproductive functions, including ovulation. Cyclooxygenase-2 (COX2) is a critical mediator of ovulation and can be induced by sphingosine-1-phosphate (S1P) through the S1P<sub>1/3</sub...

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Bibliographic Details
Main Authors: Liao-Liao Hu, Hsun-Ming Chang, Yuyin Yi, Yingtao Liu, Elizabeth L. Taylor, Li-Ping Zheng, Peter C.K. Leung
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
s1p
s1p<sub>1</sub>
ccn2
cox2
pge2
human granulosa cell
Online Access:https://www.mdpi.com/2073-4409/8/11/1445

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