Effect of Berberine against Cognitive Deficits in Rat Model of Thioacetamide-Induced Liver Cirrhosis and Hepatic Encephalopathy (Behavioral, Biochemical, Molecular and Histological Evaluations)

Effect of Berberine against Cognitive Deficits in Rat Model of Thioacetamide-Induced Liver Cirrhosis and Hepatic Encephalopathy (Behavioral, Biochemical, Molecular and Histological Evaluations)

Background: Liver cirrhosis (LC) is one of the chronic liver diseases with high disability and mortality accompanying hepatic encephalopathy (HE) followed by cognitive dysfunctions. In this work, the effect of berberine (Ber) on spatial cognition was studied in a rat model of LC induced by thioaceta...

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Bibliographic Details
Main Authors: Somayeh Hajipour, Yaghoob Farbood, Mahin Dianat, Ali Nesari, Alireza Sarkaki
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Brain Sciences
Subjects:
thioacetamide
hepatic encephalopathy
berberine
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-3425/13/6/944

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