Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease

Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease

Immunoglobulin A (IgA) is generally considered as a non-inflammatory regulator of mucosal immunity, and its importance in diversifying the gut microbiota is increasingly appreciated. IgA autoantibodies have been found in several autoimmune or chronic inflammatory diseases, but their role in pathophy...

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Bibliographic Details
Main Authors: Amelie Bos, Esil Aleyd, Lydia P. E. van der Steen, P. J. Winter, Niels Heemskerk, Stephan M. Pouw, Louis Boon, Rene J. P. Musters, Jantine E. Bakema, Cassian Sitaru, Michel Cogné, Marjolein van Egmond
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
FcαRI
CD89
IgA
neutrophils
LABD
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.732977/full

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