Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds
Q fever is a zoonotic disease caused by <i>Coxiella burnetii</i> (<i>C. burnetii</i>), a pathogen with a high capability for infection. The disease primarily affects ruminants, leading to reproductive disorders, but can also be transmitted to humans through contact with infec...
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MDPI AG
2023-09-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/18/2926 |
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| author | Jaqueline T. Bento Abdeldjalil Dahmane Sérgio Santos-Silva Nassiba Reghaissia Daniela Almeida João R. Mesquita |
| author_facet | Jaqueline T. Bento Abdeldjalil Dahmane Sérgio Santos-Silva Nassiba Reghaissia Daniela Almeida João R. Mesquita |
| author_sort | Jaqueline T. Bento |
| collection | DOAJ |
| description | Q fever is a zoonotic disease caused by <i>Coxiella burnetii</i> (<i>C. burnetii</i>), a pathogen with a high capability for infection. The disease primarily affects ruminants, leading to reproductive disorders, but can also be transmitted to humans through contact with infected animals or their products. In Algeria, Q fever is endemic, but little is known about the presence and circulation of <i>C. burnetii</i> in domestic goats. This study aimed to perform a multicentric serological analysis of <i>C. burnetii</i> antibodies in domestic goats from four provinces in the North East Region of Algeria. A total of 504 goat serum samples were collected from 77 herds, and serological analysis was performed using an indirect ELISA. The overall seroprevalence at the herd level was 35.06%, and 8.73% at the individual level. Herds with a history of abortions showed a high seropositivity rate of 88.9%. This research indicates the wide distribution of <i>C. burnetii</i> in goats in this region, suggesting the potential for zoonotic transmission to humans. Further studies and monitoring programs are essential to gain a comprehensive understanding of <i>C. burnetii</i> epidemiology in Algeria and to prevent or mitigate potential outbreaks. Awareness among practitioners and farmers is crucial to address this public health concern effectively. |
| first_indexed | 2024-03-10T23:07:19Z |
| format | Article |
| id | doaj.art-4afa0682c2ee45dd80142f8d03d28aa4 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T23:07:19Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-4afa0682c2ee45dd80142f8d03d28aa42023-11-19T09:15:31ZengMDPI AGAnimals2076-26152023-09-011318292610.3390/ani13182926Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat HerdsJaqueline T. Bento0Abdeldjalil Dahmane1Sérgio Santos-Silva2Nassiba Reghaissia3Daniela Almeida4João R. Mesquita5Department of Biology, Campus de Santiago, University of Aveiro (UA), 3810-193 Aveiro, PortugalHigher National Veterinary School, Rue Issad Abbes, El Alia, Algiers 16000, AlgeriaSchool of Medicine and Biomedical Sciences (ICBAS), University of Porto, 4200-319 Porto, PortugalLaboratory of Sciences and Living Techniques, Institute of Agronomic and Veterinary Sciences, University of Souk Ahras, Souk Ahras 41000, AlgeriaSchool of Medicine and Biomedical Sciences (ICBAS), University of Porto, 4200-319 Porto, PortugalSchool of Medicine and Biomedical Sciences (ICBAS), University of Porto, 4200-319 Porto, PortugalQ fever is a zoonotic disease caused by <i>Coxiella burnetii</i> (<i>C. burnetii</i>), a pathogen with a high capability for infection. The disease primarily affects ruminants, leading to reproductive disorders, but can also be transmitted to humans through contact with infected animals or their products. In Algeria, Q fever is endemic, but little is known about the presence and circulation of <i>C. burnetii</i> in domestic goats. This study aimed to perform a multicentric serological analysis of <i>C. burnetii</i> antibodies in domestic goats from four provinces in the North East Region of Algeria. A total of 504 goat serum samples were collected from 77 herds, and serological analysis was performed using an indirect ELISA. The overall seroprevalence at the herd level was 35.06%, and 8.73% at the individual level. Herds with a history of abortions showed a high seropositivity rate of 88.9%. This research indicates the wide distribution of <i>C. burnetii</i> in goats in this region, suggesting the potential for zoonotic transmission to humans. Further studies and monitoring programs are essential to gain a comprehensive understanding of <i>C. burnetii</i> epidemiology in Algeria and to prevent or mitigate potential outbreaks. Awareness among practitioners and farmers is crucial to address this public health concern effectively.https://www.mdpi.com/2076-2615/13/18/2926<i>Coxiella burnetii</i>Algeriagoatserology |
| spellingShingle | Jaqueline T. Bento Abdeldjalil Dahmane Sérgio Santos-Silva Nassiba Reghaissia Daniela Almeida João R. Mesquita Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds Animals <i>Coxiella burnetii</i> Algeria goat serology |
| title | Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds |
| title_full | Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds |
| title_fullStr | Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds |
| title_full_unstemmed | Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds |
| title_short | Antibody-Based Assessment of <i>Coxiella burnetii</i> Circulation in Algerian Goat Herds |
| title_sort | antibody based assessment of i coxiella burnetii i circulation in algerian goat herds |
| topic | <i>Coxiella burnetii</i> Algeria goat serology |
| url | https://www.mdpi.com/2076-2615/13/18/2926 |
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