Emergence of switch-like behavior in a large family of simple biochemical networks.
Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing the network topologies that can exhibit bistability remains a challenge, in part due to the exceed...
Main Authors: | Dan Siegal-Gaskins, Maria Katherine Mejia-Guerra, Gregory D Smith, Erich Grotewold |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-05-01
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Series: | PLoS Computational Biology |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589886/?tool=EBI |
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