Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation

Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation

<p>Abstract</p> <p>Background</p> <p>Apoptosis, neuroinflammation and blood-brain barrier (BBB) damage affect the susceptibility of the developing brain to hypoxic-ischemic (HI) insults. c-Jun N-terminal kinase (JNK) is an important mediator of insulin resistance in obe...

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Bibliographic Details
Main Authors:	Wu Hsin-Chieh, Wang Lan-Wan, Tsai Yau-Sheng, Tu Yi-Fang, Huang Chao-Ching, Ho Chien-Jung
Format:	Article
Language:	English
Published:	BMC 2011-04-01
Series:	Journal of Neuroinflammation
Online Access:	http://www.jneuroinflammation.com/content/8/1/40

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