Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin

New Candida species may cause bloodstream infections challenging current therapeutic approaches because of unpredictable susceptibility and virulence. In the present report, we describe a fungemia case due to Candida pulcherrima in a premature neonate. After full in vitro diagnostic workup, the neon...

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Main Authors: Alexandra Mpakosi, Maria Siopi, Vasiliki Falaina, Nikolaos Siafakas, Emmanuel Roilides, Maria Kimouli, Martha Theodoraki, Paraskevi Karle, Joseph Meletiadis
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Medical Mycology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753916300434
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author Alexandra Mpakosi
Maria Siopi
Vasiliki Falaina
Nikolaos Siafakas
Emmanuel Roilides
Maria Kimouli
Martha Theodoraki
Paraskevi Karle
Joseph Meletiadis
author_facet Alexandra Mpakosi
Maria Siopi
Vasiliki Falaina
Nikolaos Siafakas
Emmanuel Roilides
Maria Kimouli
Martha Theodoraki
Paraskevi Karle
Joseph Meletiadis
author_sort Alexandra Mpakosi
collection DOAJ
description New Candida species may cause bloodstream infections challenging current therapeutic approaches because of unpredictable susceptibility and virulence. In the present report, we describe a fungemia case due to Candida pulcherrima in a premature neonate. After full in vitro diagnostic workup, the neonate was successfully treated with liposomal amphotericin B and micafungin achieving rapid fungal eradication from blood.
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spelling doaj.art-4afbb529fd794cb78cb104da640275512022-12-21T19:57:27ZengElsevierMedical Mycology Case Reports2211-75392016-06-0112C242710.1016/j.mmcr.2016.08.002Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafunginAlexandra Mpakosi0Maria Siopi1Vasiliki Falaina2Nikolaos Siafakas3Emmanuel Roilides4Maria Kimouli5Martha Theodoraki6Paraskevi Karle7Joseph Meletiadis8Department of Microbiology, General Hospital of Nikaia Agios Panteleimon, Athens 18454, GreeceClinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens 12642, GreeceNeonatal Intensive Care Unit, General Hospital of Nikaia Agios Panteleimon, Athens 18454, GreeceClinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens 12642, GreeceInfectious Diseases Unit, 3rd Department of Pediatrics, Hippokration Hospital, Thessaloniki 54642, GreeceDepartment of Microbiology, General Hospital of Nikaia Agios Panteleimon, Athens 18454, GreeceNeonatal Intensive Care Unit, General Hospital of Nikaia Agios Panteleimon, Athens 18454, GreeceDepartment of Microbiology, General Hospital of Nikaia Agios Panteleimon, Athens 18454, GreeceClinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens 12642, GreeceNew Candida species may cause bloodstream infections challenging current therapeutic approaches because of unpredictable susceptibility and virulence. In the present report, we describe a fungemia case due to Candida pulcherrima in a premature neonate. After full in vitro diagnostic workup, the neonate was successfully treated with liposomal amphotericin B and micafungin achieving rapid fungal eradication from blood.http://www.sciencedirect.com/science/article/pii/S2211753916300434CandidemiaNeonateCombination antifungal therapyMicafunginLiposomal amphotericin B
spellingShingle Alexandra Mpakosi
Maria Siopi
Vasiliki Falaina
Nikolaos Siafakas
Emmanuel Roilides
Maria Kimouli
Martha Theodoraki
Paraskevi Karle
Joseph Meletiadis
Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
Medical Mycology Case Reports
Candidemia
Neonate
Combination antifungal therapy
Micafungin
Liposomal amphotericin B
title Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
title_full Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
title_fullStr Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
title_full_unstemmed Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
title_short Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
title_sort successful therapy of candida pulcherrima fungemia in a premature newborn with liposomal amphotericin b and micafungin
topic Candidemia
Neonate
Combination antifungal therapy
Micafungin
Liposomal amphotericin B
url http://www.sciencedirect.com/science/article/pii/S2211753916300434
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