Organocatalytic Asymmetric Michael Addition in Aqueous Media by a Hydrogen-Bonding Catalyst and Application for Inhibitors of GABA<sub>B</sub> Receptor

Organocatalytic Asymmetric Michael Addition in Aqueous Media by a Hydrogen-Bonding Catalyst and Application for Inhibitors of GABA<sub>B</sub> Receptor

Catalysts based on (<i>R</i>, <i>R</i>)-1,2-diphenylethylenediamine are, as chiral organic catalysts, applied to the asymmetric Michael addition to <i>α</i>, <i>β</i>-unsaturated nitroalkenes under neutral conditions. The role of an aqueous medium for...

Full description

Bibliographic Details
Main Authors: Jae Ho Shim, Yeonsun Hong, Ji Hae Kim, Hyeon Soo Kim, Deok-Chan Ha
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Catalysts
Subjects:
Michael addition
inhibitor of GABA<sub>B</sub> receptor
organic chemistry
calcium release
Online Access:https://www.mdpi.com/2073-4344/11/9/1134

Similar Items

Similar Items