Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review
Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protectiv...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-03-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/9/3/340 |
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| author | Xiao Meng Jing Zhou Cai-Ning Zhao Ren-You Gan Hua-Bin Li |
| author_facet | Xiao Meng Jing Zhou Cai-Ning Zhao Ren-You Gan Hua-Bin Li |
| author_sort | Xiao Meng |
| collection | DOAJ |
| description | Resveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer’s disease, and Parkinson’s disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases. |
| first_indexed | 2024-04-13T05:29:17Z |
| format | Article |
| id | doaj.art-4afed4403433488581134a0b68b45f20 |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-04-13T05:29:17Z |
| publishDate | 2020-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-4afed4403433488581134a0b68b45f202022-12-22T03:00:29ZengMDPI AGFoods2304-81582020-03-019334010.3390/foods9030340foods9030340Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative ReviewXiao Meng0Jing Zhou1Cai-Ning Zhao2Ren-You Gan3Hua-Bin Li4Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaSchool of Public Health, Hainan Medical University, Haikou 571199, ChinaDepartment of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, ChinaResearch Center for Plants and Human Health, Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu 610213, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaResveratrol is a bioactive compound in many foods. Since its anticancer activity was reported in 1997, its health benefits have been intensively investigated. Resveratrol has antioxidant, anti-inflammatory, immunomodulatory, glucose and lipid regulatory, neuroprotective, and cardiovascular protective effects, therefore, can protect against diverse chronic diseases, such as cardiovascular diseases (CVDs), cancer, liver diseases, obesity, diabetes, Alzheimer’s disease, and Parkinson’s disease. This review summarizes the main findings of resveratrol-related health benefits in recent epidemiological surveys, experimental studies, and clinical trials, highlighting its related molecular mechanisms. Resveratrol, therefore, has been regarded as a potent candidate for the development of nutraceuticals and pharmaceuticals to prevent and treat certain chronic diseases.https://www.mdpi.com/2304-8158/9/3/340resveratrolbioactivitiesanticanceranti-obesityantidiabetesmolecular mechanisms |
| spellingShingle | Xiao Meng Jing Zhou Cai-Ning Zhao Ren-You Gan Hua-Bin Li Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review Foods resveratrol bioactivities anticancer anti-obesity antidiabetes molecular mechanisms |
| title | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review |
| title_full | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review |
| title_fullStr | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review |
| title_full_unstemmed | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review |
| title_short | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review |
| title_sort | health benefits and molecular mechanisms of resveratrol a narrative review |
| topic | resveratrol bioactivities anticancer anti-obesity antidiabetes molecular mechanisms |
| url | https://www.mdpi.com/2304-8158/9/3/340 |
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