Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T
<b>AIM:</b> To investigate the diffusion characteristics of water of optic nerve and optic radiation in healthy adults and its related factors by diffusion tensor imaging (DTI) at 3T.<b>METHODS:</b> A total of 107 healthy volunteers performed head conventional MRI and bilater...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2013-12-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874530/ |
| _version_ | 1819143455700418560 |
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| author | Hong-Hong Sun Dong Wang Qiu-Juan Zhang Zhi-Lan Bai Ping He |
| author_facet | Hong-Hong Sun Dong Wang Qiu-Juan Zhang Zhi-Lan Bai Ping He |
| author_sort | Hong-Hong Sun |
| collection | DOAJ |
| description | <b>AIM:</b> To investigate the diffusion characteristics of water of optic nerve and optic radiation in healthy adults and its related factors by diffusion tensor imaging (DTI) at 3T.<b>METHODS:</b> A total of 107 healthy volunteers performed head conventional MRI and bilateral optic nerve and optic radiation DTI. The primary data of DTI was processed by post-processing software of DTI studio 2.3, obtaining fractional anisotropy value, mean diffusivity value, principal engine value, orthogonal engine value by measuring, and analyzed by the SPSS13.0 statistical software.<b>RESULTS:</b>The bilateral optic nerve and optic radiation fibers presented green color in directional encoded color (DEC) maps and presented high signal in fractional anisotropy (FA) maps. The FA value of the left optic nerve was 0.598±0.069 and the right was 0.593±0.065; the mean diffusivity (MD) value of the left optic nerve was (1.324±0.349)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (1.312±0.350)×10<sup>-3</sup>mm<sup>2</sup>/s; the principal engine value (λ‖) of the left optic nerve was (2.297±0.522)×10<sup>-</sup><sup>3</sup>mm<sup>2</sup>/s and the right was (2.277±0.526)×10<sup>-3</sup>mm<sup>2</sup>/s; the orthogonal engine value (λ⊥) of the left optic nerve was (0.838±0.285)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (0.830±0.280)×10<sup>-3</sup>mm<sup>2</sup>/s; the FA value of the left optic radiation was 0.636±0.057 and the right was 0.628±0.056; the mean diffusivity (MD) value of the left optic radiation was (0.907±0.103)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (0.889±0.125)×10<sup>-3</sup>mm<sup>2</sup>/s; the principal eigenvalue (λ‖) of the left optic radiation was (1.655±0.210)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (1.614±0.171)×10<sup>-3</sup>mm<sup>2</sup>/s; the orthogonal enginvalue (λ⊥) of the left optic radiation was (0.531±0.103)×10<sup>﹣3</sup>mm<sup>2</sup>/s and the right was (0.524±0.152)×10<sup>-3</sup>mm<sup>2</sup>/s. There was no obvious difference between the FA, MD, λ‖, λ⊥ of the bilateral optic radiation and the bilateral optic nerve (<i>P</i>＞0.05) and no obvious difference between male and female group. The FA, MD, λ‖, λ⊥ of the bilateral optic radiation and the bilateral optic nerve had no obvious correlations to the age.<b>CONCLUSION:</b> DTI is sensitive to the optic nerve and radiation and the relevant DTI parameters of the optic nerve and radiation are established preliminarily in this study. |
| first_indexed | 2024-12-22T12:26:31Z |
| format | Article |
| id | doaj.art-4aff98a139204143add657bb004a138b |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-22T12:26:31Z |
| publishDate | 2013-12-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-4aff98a139204143add657bb004a138b2022-12-21T18:25:47ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982013-12-016686887210.3980/j.issn.2222-3959.2013.06.22Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3THong-Hong Sun0Dong Wang1Qiu-Juan Zhang2Zhi-Lan Bai3Ping He4Department of Radiology, the Second Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Radiology, the Second Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Radiology, the Second Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Radiology, the Second Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, ChinaDepartment of Radiology, the Second Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China<b>AIM:</b> To investigate the diffusion characteristics of water of optic nerve and optic radiation in healthy adults and its related factors by diffusion tensor imaging (DTI) at 3T.<b>METHODS:</b> A total of 107 healthy volunteers performed head conventional MRI and bilateral optic nerve and optic radiation DTI. The primary data of DTI was processed by post-processing software of DTI studio 2.3, obtaining fractional anisotropy value, mean diffusivity value, principal engine value, orthogonal engine value by measuring, and analyzed by the SPSS13.0 statistical software.<b>RESULTS:</b>The bilateral optic nerve and optic radiation fibers presented green color in directional encoded color (DEC) maps and presented high signal in fractional anisotropy (FA) maps. The FA value of the left optic nerve was 0.598±0.069 and the right was 0.593±0.065; the mean diffusivity (MD) value of the left optic nerve was (1.324±0.349)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (1.312±0.350)×10<sup>-3</sup>mm<sup>2</sup>/s; the principal engine value (λ‖) of the left optic nerve was (2.297±0.522)×10<sup>-</sup><sup>3</sup>mm<sup>2</sup>/s and the right was (2.277±0.526)×10<sup>-3</sup>mm<sup>2</sup>/s; the orthogonal engine value (λ⊥) of the left optic nerve was (0.838±0.285)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (0.830±0.280)×10<sup>-3</sup>mm<sup>2</sup>/s; the FA value of the left optic radiation was 0.636±0.057 and the right was 0.628±0.056; the mean diffusivity (MD) value of the left optic radiation was (0.907±0.103)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (0.889±0.125)×10<sup>-3</sup>mm<sup>2</sup>/s; the principal eigenvalue (λ‖) of the left optic radiation was (1.655±0.210)×10<sup>-3</sup>mm<sup>2</sup>/s and the right was (1.614±0.171)×10<sup>-3</sup>mm<sup>2</sup>/s; the orthogonal enginvalue (λ⊥) of the left optic radiation was (0.531±0.103)×10<sup>﹣3</sup>mm<sup>2</sup>/s and the right was (0.524±0.152)×10<sup>-3</sup>mm<sup>2</sup>/s. There was no obvious difference between the FA, MD, λ‖, λ⊥ of the bilateral optic radiation and the bilateral optic nerve (<i>P</i>＞0.05) and no obvious difference between male and female group. The FA, MD, λ‖, λ⊥ of the bilateral optic radiation and the bilateral optic nerve had no obvious correlations to the age.<b>CONCLUSION:</b> DTI is sensitive to the optic nerve and radiation and the relevant DTI parameters of the optic nerve and radiation are established preliminarily in this study.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874530/magnetic resonance imagingdiffusion tensor imagingoptic nerveoptic radiationfractional anisotropymean diffusivitymean diffusivity |
| spellingShingle | Hong-Hong Sun Dong Wang Qiu-Juan Zhang Zhi-Lan Bai Ping He Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T International Journal of Ophthalmology magnetic resonance imaging diffusion tensor imaging optic nerve optic radiation fractional anisotropy mean diffusivity mean diffusivity |
| title | Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T |
| title_full | Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T |
| title_fullStr | Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T |
| title_full_unstemmed | Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T |
| title_short | Magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3T |
| title_sort | magnetic resonance diffusion tensor imaging of optic nerve and optic radiation in healthy adults at 3t |
| topic | magnetic resonance imaging diffusion tensor imaging optic nerve optic radiation fractional anisotropy mean diffusivity mean diffusivity |
| url | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874530/ |
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