Inferred regulons are consistent with regulator binding sequences in E. coli.

The transcriptional regulatory network (TRN) of E. coli consists of thousands of interactions between regulators and DNA sequences. Regulons are typically determined either from resource-intensive experimental measurement of functional binding sites, or inferred from analysis of high-throughput gene...

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Bibliographic Details
Main Authors: Sizhe Qiu, Xinlong Wan, Yueshan Liang, Cameron R Lamoureux, Amir Akbari, Bernhard O Palsson, Daniel C Zielinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011824&type=printable