Staphylococcus aureus Floating Biofilm Formation and Phenotype in Synovial Fluid Depends on Albumin, Fibrinogen, and Hyaluronic Acid

Staphylococcus aureus Floating Biofilm Formation and Phenotype in Synovial Fluid Depends on Albumin, Fibrinogen, and Hyaluronic Acid

Biofilms are typically studied in bacterial media that allow the study of important properties such as bacterial growth. However, the results obtained in such media cannot take into account the bacterial localization/clustering caused by bacteria–protein interactions in vivo and the accompanying alt...

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Bibliographic Details
Main Authors: Samantha Knott, Dylan Curry, Neil Zhao, Pallavi Metgud, Sana S. Dastgheyb, Caroline Purtill, Marc Harwood, Antonia F. Chen, Thomas P. Schaer, Michael Otto, Noreen J. Hickok
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
biofilm
synovial fluid
antibiotic tolerance
virulence factors
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.655873/full

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