RNA-binding proteins direct myogenic cell fate decisions

RNA-binding proteins direct myogenic cell fate decisions

RNA-binding proteins (RBPs), essential for skeletal muscle regeneration, cause muscle degeneration and neuromuscular disease when mutated. Why mutations in these ubiquitously expressed RBPs orchestrate complex tissue regeneration and direct cell fate decisions in skeletal muscle remains poorly under...

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Bibliographic Details
Main Authors: Joshua R Wheeler, Oscar N Whitney, Thomas O Vogler, Eric D Nguyen, Bradley Pawlikowski, Evan Lester, Alicia Cutler, Tiffany Elston, Nicole Dalla Betta, Kevin R Parker, Kathryn E Yost, Hannes Vogel, Thomas A Rando, Howard Y Chang, Aaron M Johnson, Roy Parker, Bradley B Olwin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
RNA-binding protein
skeletal muscle
regeneration
RNA splicing
splicing network
post-transcriptional regulation
Online Access:https://elifesciences.org/articles/75844

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