Genetic analysis of the X chromosome in people with Lewy body dementia nominates new risk loci

Genetic analysis of the X chromosome in people with Lewy body dementia nominates new risk loci

Abstract Sex influences the prevalence and symptoms of Lewy body dementia (LBD). However, genome-wide association studies typically focus on autosomal variants and exclude sex-specific risk factors. We addressed this gap by performing an X chromosome-wide association study using whole-genome sequenc...

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Bibliographic Details
Main Authors: Ece Bayram, Paolo Reho, Irene Litvan, International LBD Genomics Consortium, Jinhui Ding, J. Raphael Gibbs, Clifton L. Dalgard, Bryan J. Traynor, Sonja W. Scholz, Ruth Chia
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00649-7

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