The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report

Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion o...

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Main Authors: Joana Barradas Lopes, Moises Labrador-Horrilo, Borja Bartolomé, Leonor Cunha
Format: Article
Language:English
Published: Ordem dos Médicos 2022-05-01
Series:Acta Médica Portuguesa
Subjects:
Online Access:https://actamedicaportuguesa.com/revista/index.php/amp/article/view/15483
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author Joana Barradas Lopes
Moises Labrador-Horrilo
Borja Bartolomé
Leonor Cunha
author_facet Joana Barradas Lopes
Moises Labrador-Horrilo
Borja Bartolomé
Leonor Cunha
author_sort Joana Barradas Lopes
collection DOAJ
description Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.
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spelling doaj.art-4b0d3f8af79b47b2a681f676ca74f69e2022-12-22T03:37:34ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582022-05-0135510.20344/amp.154835373The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case ReportJoana Barradas Lopes0Moises Labrador-Horrilo1Borja Bartolomé2Leonor Cunha3Department of Immunoallergology. Centro Hospitalar de Vila Nova de Gaia/Espinho. Vila Nova de Gaia.Department of Allergy. Hospital Vall de’Hebron UAB. Barcelona.Research and Development Department of Roxall. Bilbao.Department of Immunoallergology. Centro Hospital Universitário do Porto. Porto. Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations. https://actamedicaportuguesa.com/revista/index.php/amp/article/view/15483Cats/immunologyFood Hypersensitivity/immunologyMeat/adverse effectsSerum Albumin/immunologySwine/immunology
spellingShingle Joana Barradas Lopes
Moises Labrador-Horrilo
Borja Bartolomé
Leonor Cunha
The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
Acta Médica Portuguesa
Cats/immunology
Food Hypersensitivity/immunology
Meat/adverse effects
Serum Albumin/immunology
Swine/immunology
title The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
title_full The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
title_fullStr The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
title_full_unstemmed The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
title_short The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report
title_sort role of molecular allergens in the diagnosis of cat pork syndrome an unusual case report
topic Cats/immunology
Food Hypersensitivity/immunology
Meat/adverse effects
Serum Albumin/immunology
Swine/immunology
url https://actamedicaportuguesa.com/revista/index.php/amp/article/view/15483
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