NLRP6 Serves as a Negative Regulator of Neutrophil Recruitment and Function During Streptococcus pneumoniae Infection

NLRP6 Serves as a Negative Regulator of Neutrophil Recruitment and Function During Streptococcus pneumoniae Infection

Streptococcus pneumoniae is an invasive pathogen with high morbidity and mortality in the immunocompromised children and elderly. NOD-like receptor family pyrin domain containing 6 (NLRP6) plays an important role in the host innate immune response against pathogen infections. Our previous studies ha...

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Bibliographic Details
Main Authors: Qi Tao, Dongyi Xu, Kaixiang Jia, Xinrui Cao, Chao Ye, Sanlei Xie, Dong-Liang Hu, Lianci Peng, Rendong Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus pneumoniae
NLRP6
neutrophils
neutrophil extracellular traps
host defense
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.898559/full

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