Molecular and Brain Volume Changes Following Aerobic Exercise, Cognitive and Combined Training in Physically Inactive Healthy Late-Middle-Aged Adults: The Projecte Moviment Randomized Controlled Trial

Molecular and Brain Volume Changes Following Aerobic Exercise, Cognitive and Combined Training in Physically Inactive Healthy Late-Middle-Aged Adults: The Projecte Moviment Randomized Controlled Trial

Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week (5 days per week—45 min per day) multi-domain, single-blind, proof-of-concept randomi...

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Bibliographic Details
Main Authors: Alba Castells-Sánchez, Francesca Roig-Coll, Rosalía Dacosta-Aguayo, Noemí Lamonja-Vicente, Pere Torán-Monserrat, Guillem Pera, Alberto García-Molina, José Maria Tormos, Pilar Montero-Alía, Antonio Heras-Tébar, Juan José Soriano-Raya, Cynthia Cáceres, Sira Domènech, Marc Via, Kirk I. Erickson, Maria Mataró
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Human Neuroscience
Subjects:
aerobic exercise
computerized cognitive training
combined training
brain volume
BDNF
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2022.854175/full

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