Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens?
We have previously reported a significant association between the single-nucleotide polymorphism (SNP; g.420 C>A) in the cholecystokinin type A receptor gene (CCKAR) and the growth traits of Hinai-dori, a breed of chicken that is indigenous to Japan. Moreover, we have demonstrated that the mi...
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2020-04-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/57/2/57_0190041/_html/-char/en |
| _version_ | 1827939002750074880 |
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| author | Kazuhiro Rikimaru Yuki Sato Yukari Ito Shiori Fukuda Senetsu Sasaki Hideaki Takahashi |
| author_facet | Kazuhiro Rikimaru Yuki Sato Yukari Ito Shiori Fukuda Senetsu Sasaki Hideaki Takahashi |
| author_sort | Kazuhiro Rikimaru |
| collection | DOAJ |
| description | We have previously reported a significant association between the single-nucleotide polymorphism (SNP; g.420 C>A) in the cholecystokinin type A receptor gene (CCKAR) and the growth traits of Hinai-dori, a breed of chicken that is indigenous to Japan. Moreover, we have demonstrated that the minor allele of this SNP improved the growth rate in a low-growth line of the Hinai-dori breed. Hence, in the present study, we verified the association between this SNP and the growth traits of the Hinai-jidori chicken: a cross between a Hinai-dori sire and Rhode Island Red dam. In addition, we verified whether the growth rate was improved in Hinai-jidori chickens produced from the parent stocks in which the SNP A/A genotype was fixed by selection (improved Hinai-jidori chickens). The Hinai-jidori female chicks at 4 weeks of age, were subdivided into three genotypic groups (A/A, A/C, and C/C), with 20 chicks in each group, and reared in an open-sided poultry shed until 23 weeks of age. The results showed that the body weight at 23 weeks of age and the average daily gain after 14 weeks of age were significantly higher in group A/A than in group C/C. Subsequently, the improved and the conventional Hinai-jidori chickens were reared until they reached 22 weeks of age to verify the effects on their growth traits. The body weight of the improved Hinai-jidori chickens at 22 weeks was significantly greater than the conventional Hinai-jidori chickens. Moreover, the association between the SNP and body weights of Hinai-jidori chickens at market age (24 weeks) on the production farms showed that the A allele was significantly superior to the C allele. In conclusion, the CCKAR g.420 C>A SNP improves the growth rate of commercial Hinai-jidori chickens and could be a candidate marker for improving the growth performance in selective breeding of Hinai-jidori chickens. |
| first_indexed | 2024-03-13T08:46:54Z |
| format | Article |
| id | doaj.art-4b11feca3b19487aa9ef14d70905c993 |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:46:54Z |
| publishDate | 2020-04-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-4b11feca3b19487aa9ef14d70905c9932023-05-30T01:15:58ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862020-04-015729910610.2141/jpsa.0190041jpsaIs a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens?Kazuhiro Rikimaru0Yuki Sato1Yukari Ito2Shiori Fukuda3Senetsu Sasaki4Hideaki Takahashi5Akita Prefectural Livestock Experiment StationAkita Prefectural Livestock Experiment StationAkita Prefectural Livestock Experiment StationAkita Prefectural Livestock Experiment StationAkita Prefectural Livestock Experiment StationInstitute of Livestock and Grassland Science, NAROWe have previously reported a significant association between the single-nucleotide polymorphism (SNP; g.420 C>A) in the cholecystokinin type A receptor gene (CCKAR) and the growth traits of Hinai-dori, a breed of chicken that is indigenous to Japan. Moreover, we have demonstrated that the minor allele of this SNP improved the growth rate in a low-growth line of the Hinai-dori breed. Hence, in the present study, we verified the association between this SNP and the growth traits of the Hinai-jidori chicken: a cross between a Hinai-dori sire and Rhode Island Red dam. In addition, we verified whether the growth rate was improved in Hinai-jidori chickens produced from the parent stocks in which the SNP A/A genotype was fixed by selection (improved Hinai-jidori chickens). The Hinai-jidori female chicks at 4 weeks of age, were subdivided into three genotypic groups (A/A, A/C, and C/C), with 20 chicks in each group, and reared in an open-sided poultry shed until 23 weeks of age. The results showed that the body weight at 23 weeks of age and the average daily gain after 14 weeks of age were significantly higher in group A/A than in group C/C. Subsequently, the improved and the conventional Hinai-jidori chickens were reared until they reached 22 weeks of age to verify the effects on their growth traits. The body weight of the improved Hinai-jidori chickens at 22 weeks was significantly greater than the conventional Hinai-jidori chickens. Moreover, the association between the SNP and body weights of Hinai-jidori chickens at market age (24 weeks) on the production farms showed that the A allele was significantly superior to the C allele. In conclusion, the CCKAR g.420 C>A SNP improves the growth rate of commercial Hinai-jidori chickens and could be a candidate marker for improving the growth performance in selective breeding of Hinai-jidori chickens.https://www.jstage.jst.go.jp/article/jpsa/57/2/57_0190041/_html/-char/enchickencholecystokinin type a receptor genegrowth traithinai-jidorisingle-nucleotide polymorphism |
| spellingShingle | Kazuhiro Rikimaru Yuki Sato Yukari Ito Shiori Fukuda Senetsu Sasaki Hideaki Takahashi Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? The Journal of Poultry Science chicken cholecystokinin type a receptor gene growth trait hinai-jidori single-nucleotide polymorphism |
| title | Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? |
| title_full | Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? |
| title_fullStr | Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? |
| title_full_unstemmed | Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? |
| title_short | Is a Single Nucleotide Polymorphism Marker in the Cholecystokinin A Receptor Gene Practically Suitable for Improving the Growth Traits of Hinai-jidori Chickens? |
| title_sort | is a single nucleotide polymorphism marker in the cholecystokinin a receptor gene practically suitable for improving the growth traits of hinai jidori chickens |
| topic | chicken cholecystokinin type a receptor gene growth trait hinai-jidori single-nucleotide polymorphism |
| url | https://www.jstage.jst.go.jp/article/jpsa/57/2/57_0190041/_html/-char/en |
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