Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses

Pretreatment with an antibiotics cocktail enhances the protective effect of probiotics by regulating SCFA metabolism and Th1/Th2/Th17 cell immune responses

Abstract Background Probiotics are a potentially effective therapy for inflammatory bowel disease (IBD); IBD is linked to impaired gut microbiota and intestinal immunity. However, the utilization of an antibiotic cocktail (Abx) prior to the probiotic intervention remains controversial. This study ai...

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Bibliographic Details
Main Authors: Jing Xu, Haoming Xu, Xue Guo, Hailan Zhao, Jiaqi Wang, Jianhong Li, Jie He, Hongli Huang, Chen Huang, Chong Zhao, Yingfei Li, Youlian Zhou, Yao Peng, Yuqiang Nie
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Microbiology
Subjects:
Antibiotic cocktails
Clostridium butyricum Miyairi588
Gut microbiota
Short-chain fatty acids
Th1/Th2/Th17 response
Online Access:https://doi.org/10.1186/s12866-024-03251-2

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