Delayed Recognition of Levetiracetam-induced Pancytopenia
Blood dyscrasias associated with levetiracetam use can be difficult to identify, especially when other potential differential diagnoses are concurrently present. Here we present a 57-year-old man with metastatic adenocarcinoma of unknown primary origin on levetiracetam who initially presented with a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2021-03-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/2449 |
| _version_ | 1828893095775698944 |
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| author | Mohammad Ammad Ud Din Syed Ather Hussain Amy Bodrog |
| author_facet | Mohammad Ammad Ud Din Syed Ather Hussain Amy Bodrog |
| author_sort | Mohammad Ammad Ud Din |
| collection | DOAJ |
| description | Blood dyscrasias associated with levetiracetam use can be difficult to identify, especially when other potential differential diagnoses are concurrently present. Here we present a 57-year-old man with metastatic adenocarcinoma of unknown primary origin on levetiracetam who initially presented with an in-stent thrombosis of the right external iliac vein and then developed worsening thrombocytopenia followed by pancytopenia. Levetiracetam was not identified as the culprit until other causes like platelet consumption, heparin-induced thrombocytopenia, idiopathic immune thrombocytopenic purpura, and bone marrow involvement by metastatic disease were ruled out. |
| first_indexed | 2024-12-13T13:47:39Z |
| format | Article |
| id | doaj.art-4b1f60a4e3a14953a66f6c9be3be130a |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-12-13T13:47:39Z |
| publishDate | 2021-03-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-4b1f60a4e3a14953a66f6c9be3be130a2022-12-21T23:43:20ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942021-03-0110.12890/2021_0024492065Delayed Recognition of Levetiracetam-induced PancytopeniaMohammad Ammad Ud Din0https://orcid.org/0000-0001-9083-636XSyed Ather Hussain1Amy Bodrog2Internal Medicine, Rochester General Hospital, Rochester, New York, USAInternal Medicine, Rochester General Hospital, Rochester, New York, USAHematology/Oncology, Rochester General Hospital, Rochester, New York, USABlood dyscrasias associated with levetiracetam use can be difficult to identify, especially when other potential differential diagnoses are concurrently present. Here we present a 57-year-old man with metastatic adenocarcinoma of unknown primary origin on levetiracetam who initially presented with an in-stent thrombosis of the right external iliac vein and then developed worsening thrombocytopenia followed by pancytopenia. Levetiracetam was not identified as the culprit until other causes like platelet consumption, heparin-induced thrombocytopenia, idiopathic immune thrombocytopenic purpura, and bone marrow involvement by metastatic disease were ruled out.https://www.ejcrim.com/index.php/EJCRIM/article/view/2449drug-induced-pancytopeniathrombocytopenialevetiracetamhematologyanti-epileptics |
| spellingShingle | Mohammad Ammad Ud Din Syed Ather Hussain Amy Bodrog Delayed Recognition of Levetiracetam-induced Pancytopenia European Journal of Case Reports in Internal Medicine drug-induced-pancytopenia thrombocytopenia levetiracetam hematology anti-epileptics |
| title | Delayed Recognition of Levetiracetam-induced Pancytopenia |
| title_full | Delayed Recognition of Levetiracetam-induced Pancytopenia |
| title_fullStr | Delayed Recognition of Levetiracetam-induced Pancytopenia |
| title_full_unstemmed | Delayed Recognition of Levetiracetam-induced Pancytopenia |
| title_short | Delayed Recognition of Levetiracetam-induced Pancytopenia |
| title_sort | delayed recognition of levetiracetam induced pancytopenia |
| topic | drug-induced-pancytopenia thrombocytopenia levetiracetam hematology anti-epileptics |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/2449 |
| work_keys_str_mv | AT mohammadammaduddin delayedrecognitionoflevetiracetaminducedpancytopenia AT syedatherhussain delayedrecognitionoflevetiracetaminducedpancytopenia AT amybodrog delayedrecognitionoflevetiracetaminducedpancytopenia |