Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia
Objective: To analyse the clinic characteristics, risk factors and evolution of the first cohort of hospitalised patients with confirmed infection by COVID-19 in 5 Colombian institutions. Materials and methods: Is a retrospective observational study of consecutive hospitalized patients with a diagno...
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| Format: | Article |
| Language: | English |
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Asociación Colombiana de Infectología
2021-04-01
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| Series: | Infectio |
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| _version_ | 1811210769170169856 |
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| author | Nancy Yomayusa-Gonzalez |
| author_facet | Nancy Yomayusa-Gonzalez |
| author_sort | Nancy Yomayusa-Gonzalez |
| collection | DOAJ |
| description | Objective: To analyse the clinic characteristics, risk factors and evolution of the first cohort of hospitalised patients with confirmed infection by COVID-19 in 5 Colombian institutions. Materials and methods: Is a retrospective observational study of consecutive hospitalized patients with a diagnosis of COVID-19 confirmed from March 01 to May 30, 2020 in Colombia. Results: A total of 44 patients were included. The median age was 62 years. 43.2% had a history of smoking, while 69.8% were overweight or obese. 88.6% had at least one comorbidity and 52.3% had three or more comorbidities. Hypertension and dyslipidaemia were the most frequent comorbidities (40.9% and 34.1%, respectively). The 30-day mortality rate was 47.7% with a median of 11 days. The composite outcome occurred in the 36.4%. The biomarkers associated with mor-tality risk included troponin higher than 14 ng/L (RR: 5.25; 95% CI 1.37-20.1, p = 0.004) and D-dimer higher than 1000 ng/ml (RR: 3.0; 95% CI 1.4-6.3, p = 0.008). Conclusions: The clinical course of SARS-CoV-2 infection in hospitalized Colombian was characterised by a more advanced stage of the infection. |
| first_indexed | 2024-04-12T05:00:00Z |
| format | Article |
| id | doaj.art-4b21507fc65c424eb7e7d37f38c9e69b |
| institution | Directory Open Access Journal |
| issn | 0123-9392 |
| language | English |
| last_indexed | 2024-04-12T05:00:00Z |
| publishDate | 2021-04-01 |
| publisher | Asociación Colombiana de Infectología |
| record_format | Article |
| series | Infectio |
| spelling | doaj.art-4b21507fc65c424eb7e7d37f38c9e69b2022-12-22T03:47:00ZengAsociación Colombiana de InfectologíaInfectio0123-93922021-04-01254262269https://doi.org/10.22354/in.v25i4.958Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in ColombiaNancy Yomayusa-Gonzalez0 Keralty, Instituto Global de Excelencia Clínica, Bogotá DC, Colombia. Grupo De Investigación Traslacional Keralty, Bogotá DC, Colombia. Fundación Universitaria Sanitas, Bogotá DC, ColombiObjective: To analyse the clinic characteristics, risk factors and evolution of the first cohort of hospitalised patients with confirmed infection by COVID-19 in 5 Colombian institutions. Materials and methods: Is a retrospective observational study of consecutive hospitalized patients with a diagnosis of COVID-19 confirmed from March 01 to May 30, 2020 in Colombia. Results: A total of 44 patients were included. The median age was 62 years. 43.2% had a history of smoking, while 69.8% were overweight or obese. 88.6% had at least one comorbidity and 52.3% had three or more comorbidities. Hypertension and dyslipidaemia were the most frequent comorbidities (40.9% and 34.1%, respectively). The 30-day mortality rate was 47.7% with a median of 11 days. The composite outcome occurred in the 36.4%. The biomarkers associated with mor-tality risk included troponin higher than 14 ng/L (RR: 5.25; 95% CI 1.37-20.1, p = 0.004) and D-dimer higher than 1000 ng/ml (RR: 3.0; 95% CI 1.4-6.3, p = 0.008). Conclusions: The clinical course of SARS-CoV-2 infection in hospitalized Colombian was characterised by a more advanced stage of the infection.covid-19risk factorsmortality |
| spellingShingle | Nancy Yomayusa-Gonzalez Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia Infectio covid-19 risk factors mortality |
| title | Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia |
| title_full | Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia |
| title_fullStr | Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia |
| title_full_unstemmed | Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia |
| title_short | Clinical course, biomarkers, management and outcomes of patients hospitalised due to COVID-19 in Colombia |
| title_sort | clinical course biomarkers management and outcomes of patients hospitalised due to covid 19 in colombia |
| topic | covid-19 risk factors mortality |
| work_keys_str_mv | AT nancyyomayusagonzalez clinicalcoursebiomarkersmanagementandoutcomesofpatientshospitalisedduetocovid19incolombia |