3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis

3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis

Aims: The use of 3D-printed titanium implant (DT) can effectively guide bone regeneration. DT triggers a continuous host immune reaction, including macrophage type 1 polarization, that resists osseointegration. Interleukin 4 (IL4) is a specific cytokine modulating osteogenic capability that switches...

Full description

Bibliographic Details
Main Authors: Da-Wang Zhao, Bing Ren, Hong-Wei Wang, Xiao Zhang, Ming-Zhi Yu, Lei Cheng, Yuan-Hua Sang, Shuai-Shuai Cao, Florian M. Thieringer, Dong Zhang, Yi Wan, Chao Liu
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-07-01
Series:Bone & Joint Research
Subjects:
interleukin 4
3d-printed titanium implant
macrophage polarization
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.107.BJR-2020-0334.R4

Similar Items

Similar Items