Construction of cuproptosis-related gene signature to predict the prognosis and immunotherapy efficacy of patients with bladder cancer through bioinformatics analysis and experimental validation

Construction of cuproptosis-related gene signature to predict the prognosis and immunotherapy efficacy of patients with bladder cancer through bioinformatics analysis and experimental validation

Background: A new form of cell death, copper-dependent cell death (termed cuproptosis), was illustrated in a recent scientific study. However, the biological function or prognostic value of cuproptosis regulators in bladder cancer (BLCA) remains unknown.Materials and Methods: Sequencing data obtaine...

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Bibliographic Details
Main Authors: Zijian Liu, Fubin Zhu, Pu Zhang, Bei Qian, Weihui Liu, Yajun Xiao, Nianyong Chen, Qingliu He, Jianghong Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
cuproptosis
tumor microenvironment
bladder cancer
immunotherapy
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1074981/full

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