Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia

Apathy is a quantitive reduction of goal-directed activity either in behavioural, cognitive, emotional or social dimension in comparison to the person’s previous level of functioning in these areas. Apathy is prevalent across many neurodegenerative, neurological, and psychiatric disorders. It repres...

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Main Author: E. Fernandez-Egea
Format: Article
Language:English
Published: Cambridge University Press 2021-04-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933821001607/type/journal_article
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author E. Fernandez-Egea
author_facet E. Fernandez-Egea
author_sort E. Fernandez-Egea
collection DOAJ
description Apathy is a quantitive reduction of goal-directed activity either in behavioural, cognitive, emotional or social dimension in comparison to the person’s previous level of functioning in these areas. Apathy is prevalent across many neurodegenerative, neurological, and psychiatric disorders. It represents the most common behavioural and psychological symptom in people with Alzheimer’s Disease and is often observed in Parkinson’s disease, vascular dementia, stroke, traumatic brain injury, amyotrophic lateral sclerosis/motor neuron disease, frontotemporal dementia, progressive supranuclear palsy, major depression, and schizophrenia. However, the definition and terminology employed to refer to apathy can vary in the context of different conditions and specialities and the diagnostic criteria have evolved. Additionally, the term apathy is employed to describe both a symptom and a syndrome. Indeed, little progress has been achieved in assessing the validity of the same construct across different disorders (eg. neurodegenerative disorders, schizophrenia or affective disorders). In 2018, a new version of the diagnostic criteria for apathy (DCA) in neuropsychiatric disorders was published. The validity of this new consensus has yet to be assessed among all relevant populations, including schizophrenia. Six European centres (Naples, Geneve, Nice, Rennes, Barcelona, Cambridge) aimed to test the prevalence of apathy, measured with the 2018 DCA, in patients diagnosed with schizophrenia. As a second aim, we focused on the relationship between DCA and other measures of apathy and negative symptoms in schizophrenia (BNSS and PANSS). In this talk, we will compare the preliminary findings of this pan-European study in schizophrenia patients with previous studies on neurodegenerative disorders.
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spelling doaj.art-4b2900be914544c89752b4774cce83642023-11-17T05:06:46ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S50S5110.1192/j.eurpsy.2021.160Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophreniaE. Fernandez-Egea0Department Of Psychiatry, University of Cambridge, Cambridge, United KingdomApathy is a quantitive reduction of goal-directed activity either in behavioural, cognitive, emotional or social dimension in comparison to the person’s previous level of functioning in these areas. Apathy is prevalent across many neurodegenerative, neurological, and psychiatric disorders. It represents the most common behavioural and psychological symptom in people with Alzheimer’s Disease and is often observed in Parkinson’s disease, vascular dementia, stroke, traumatic brain injury, amyotrophic lateral sclerosis/motor neuron disease, frontotemporal dementia, progressive supranuclear palsy, major depression, and schizophrenia. However, the definition and terminology employed to refer to apathy can vary in the context of different conditions and specialities and the diagnostic criteria have evolved. Additionally, the term apathy is employed to describe both a symptom and a syndrome. Indeed, little progress has been achieved in assessing the validity of the same construct across different disorders (eg. neurodegenerative disorders, schizophrenia or affective disorders). In 2018, a new version of the diagnostic criteria for apathy (DCA) in neuropsychiatric disorders was published. The validity of this new consensus has yet to be assessed among all relevant populations, including schizophrenia. Six European centres (Naples, Geneve, Nice, Rennes, Barcelona, Cambridge) aimed to test the prevalence of apathy, measured with the 2018 DCA, in patients diagnosed with schizophrenia. As a second aim, we focused on the relationship between DCA and other measures of apathy and negative symptoms in schizophrenia (BNSS and PANSS). In this talk, we will compare the preliminary findings of this pan-European study in schizophrenia patients with previous studies on neurodegenerative disorders.https://www.cambridge.org/core/product/identifier/S0924933821001607/type/journal_articlemotivationnegative symptomsrewardapathy
spellingShingle E. Fernandez-Egea
Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
European Psychiatry
motivation
negative symptoms
reward
apathy
title Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
title_full Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
title_fullStr Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
title_full_unstemmed Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
title_short Is apathy a true trans-diagnostic construct? preliminary findings of the european study on apathy in schizophrenia
title_sort is apathy a true trans diagnostic construct preliminary findings of the european study on apathy in schizophrenia
topic motivation
negative symptoms
reward
apathy
url https://www.cambridge.org/core/product/identifier/S0924933821001607/type/journal_article
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