<i>APOE</i> Variants in an Iberian Alzheimer Cohort Detected through an Optimized Sanger Sequencing Protocol

<i>APOE</i> Variants in an Iberian Alzheimer Cohort Detected through an Optimized Sanger Sequencing Protocol

The primary genetic risk factor for late onset Alzheimer’s disease (LOAD) is the <i>APOE4</i> allele of <i>Apolipoprotein E</i> (<i>APOE</i>) gene. The three most common variants of <i>APOE</i> are determined by single nucleotide polymorphisms (SNPs) r...

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Bibliographic Details
Main Authors: Ricardo D. González, Iva Gomes, Catarina Gomes, Rita Rocha, Luís Durães, Patrícia Sousa, Manuel Figueruelo, Maria Rodríguez, Carmen Pita, Roberto Hornero, Carlos Gómez, Alexandra M. Lopes, Nádia Pinto, Sandra Martins
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
late onset Alzheimer’s disease (LOAD)
<i>Apolipoprotein E</i> (<i>APOE</i>)
rs429358
rs7412
sanger sequencing
disease risk
Online Access:https://www.mdpi.com/2073-4425/12/1/4

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