TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL

TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL

Spermatogonial stem cells (SSCs) are the initial cells for the spermatogenesis. Although much progress has been made on uncovering a number of modulators for the SSC fate decisions in rodents, the genes mediating human SSCs remain largely unclear. Here we report, for the first time, that TCF3, a mem...

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Bibliographic Details
Main Authors: Dai Zhou, Jingyu Fan, Zhizhong Liu, Ruiling Tang, Xingming Wang, Hao Bo, Fang Zhu, Xueheng Zhao, Zenghui Huang, Liu Xing, Ke Tao, Han Zhang, Hongchuan Nie, Huan Zhang, Wenbing Zhu, Zuping He, Liqing Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TCF3
human spermatogonial stem cells
proliferation
apoptosis
PODXL
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.695545/full

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